Technology Process of 6-benzyl-6,7-dihydro-6-methyl-5H-dibenzo<1,5>thiazocinium-5,5,7,7-d4 bromide
There total 10 articles about 6-benzyl-6,7-dihydro-6-methyl-5H-dibenzo<1,5>thiazocinium-5,5,7,7-d4 bromide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / dioxane; H2O / 1 h
2: LiAlD4 / tetrahydrofuran / Ambient temperature
3: phosphorus tribromide / CHCl3 / 1.) ice-cooled, 2 h, 2.) room temp., 17 h, 3.) reflux, 2 h
4: 65 percent / 72 h / 60 °C
With
lithium aluminium deuteride; phosphorus tribromide;
In
tetrahydrofuran; 1,4-dioxane; chloroform; water;
DOI:10.1021/jo00321a020
- Guidance literature:
-
Multi-step reaction with 8 steps
1: thionyl chloride / 5 h / 60 °C
2: 0.5 h / Heating
3: 37 percent / KOH / ethanol / 96 h / Ambient temperature
4: 20.1 g / thionyl chloride
5: 96 percent / dioxane; H2O / 1 h
6: LiAlD4 / tetrahydrofuran / Ambient temperature
7: phosphorus tribromide / CHCl3 / 1.) ice-cooled, 2 h, 2.) room temp., 17 h, 3.) reflux, 2 h
8: 65 percent / 72 h / 60 °C
With
potassium hydroxide; thionyl chloride; lithium aluminium deuteride; phosphorus tribromide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; chloroform; water;
DOI:10.1021/jo00321a020
