4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole

Base Information

• Chemical Name: 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole
• CAS No.: 1393528-97-6
• Molecular Formula: C₁₄H₁₇Br₂F₂N₃
• Molecular Weight: 425.114
• Mol file: 1393528-97-6.mol

Synonyms:

Chemical Property of 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

4,7-Dibromo-5,6-difluoro-2-octyl-2H-benzo[d][1,2,3]triazole 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole

There total 5 articles about 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4,7-bis(trimethylsilyl)-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]-triazole → 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole (1393528-97-6)

Guidance literature:

With bromine; In chloroform; at 60 ℃; for 24h;

DOI:10.1021/cm3017006

Reference yield:

2-amino-4,5-difluoroaniline (76179-40-3) → 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole (1393528-97-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium nitrite; acetic acid / water / 1 h / 5 - 20 °C

2.1: potassium tert-butylate / methanol / 24 h / Reflux

3.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

3.2: 3 h / -78 °C / Inert atmosphere

4.1: bromine / chloroform / 24 h / 60 °C

With potassium tert-butylate; bromine; acetic acid; lithium diisopropyl amide; sodium nitrite; In tetrahydrofuran; methanol; chloroform; water;

DOI:10.1021/cm3017006

Reference yield:

5,6-difluoro-1H-benzo[d][1,2,3]triazole (610257-65-3) → 4,7-dibromo-2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole (1393528-97-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium tert-butylate / methanol / 24 h / Reflux

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 3 h / -78 °C / Inert atmosphere

3.1: bromine / chloroform / 24 h / 60 °C

With potassium tert-butylate; bromine; lithium diisopropyl amide; In tetrahydrofuran; methanol; chloroform;

DOI:10.1021/cm3017006

upstream raw materials:

2-amino-4,5-difluoroaniline

5,6-difluoro-1H-benzo[d][1,2,3]triazole

2-(1-octyl)-5,6-difluoro-2H-benzo[d][1,2,3]triazole

4,5-difluoro-2-nitroaniline