C₁₃H₁₇NO

Base Information

• Chemical Name: C₁₃H₁₇NO
• CAS No.: 1606993-65-0
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.284
• Mol file: 1606993-65-0.mol

Synonyms:

Chemical Property of C₁₃H₁₇NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₇NO

There total 4 articles about C₁₃H₁₇NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-aniline (104-94-9) → C13H17NO (1606993-65-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 4 h / 100 °C

2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -78 - 20 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / -78 °C / Inert atmosphere

4.1: tetrahydrofuran; hexane / 20 h / 20 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; diisobutylaluminium hydride; sodium hydrogencarbonate; lithium diisopropyl amide; In tetrahydrofuran; hexane; water; N,N-dimethyl-formamide; toluene;

DOI:10.1021/jo500249c

Reference yield:

C13H17NO3 (1606993-67-2) → C13H17NO (1606993-65-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere

1.2: 0.5 h / -78 - 20 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / -78 °C / Inert atmosphere

3.1: tetrahydrofuran; hexane / 20 h / 20 °C / Inert atmosphere

With diisobutylaluminium hydride; lithium diisopropyl amide; In tetrahydrofuran; hexane; toluene;

DOI:10.1021/jo500249c

Reference yield:

N-(4-methoxyphenyl)-2-ethoxycarbonyl-2-methylazetidine (1606993-73-0) → C13H17NO (1606993-65-0)

Guidance literature:

Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 2 h / -78 °C / Inert atmosphere

2: tetrahydrofuran; hexane / 20 h / 20 °C / Inert atmosphere

With diisobutylaluminium hydride; In tetrahydrofuran; hexane; toluene;

DOI:10.1021/jo500249c

upstream raw materials:

4-methoxy-aniline

C₁₃H₁₇NO₃

N-(4-methoxyphenyl)-2-ethoxycarbonyl-2-methylazetidine

Methylenetriphenylphosphorane