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H-L-Tyr-D-Ala-OMe?TFA

Base Information Edit
  • Chemical Name:H-L-Tyr-D-Ala-OMe?TFA
  • CAS No.:1421237-43-5
  • Molecular Formula:C2HF3O2*C13H18N2O4
  • Molecular Weight:380.321
  • Hs Code.:
  • Mol file:1421237-43-5.mol
H-L-Tyr-D-Ala-OMe?TFA

Synonyms:

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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of H-L-Tyr-D-Ala-OMe?TFA Edit
Chemical Property:
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Technology Process of H-L-Tyr-D-Ala-OMe?TFA

There total 1 articles about H-L-Tyr-D-Ala-OMe?TFA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide; N-ethyl-N,N-diisopropylamine / dichloromethane
2: water / diethyl ether / Cooling
With water; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In diethyl ether; dichloromethane;
DOI:10.1002/anie.201207730
Guidance literature:
H-L-Tyr-D-Ala-OMe?TFA; acetic anhydride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 4h;
With sodium hydroxide; In water; isopropyl alcohol;
DOI:10.1002/anie.201207730
Guidance literature:
With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 4h; Overall yield = 337.3 mg;
DOI:10.1002/anie.201207730
upstream raw materials:

Boc-Tyr-OH

Downstream raw materials:

Ac-L-Tyr-D-Ala-OMe

(L,D)-Ac-Tyr(Ac)-D-Ala-OMe

Ac-L-Tyr-D-Ala-OH

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