83049-21-2Relevant academic research and scientific papers
5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution
Danger, Grégoire,Michaut, Arthur,Bucchi, Manon,Boiteau, Laurent,Canal, Justine,Plasson, Rapha?l,Pascal, Robert
, p. 611 - 614 (2013/02/23)
The early days: Although considered a species to be avoided in peptide chemistry, the intermediacy of 5(4H)-oxazolones is demonstrated to be essential for the formation of peptides through cyanamide and carbodiimide activation in aqueous solution (see sch
SYNTHESIS OF CHIRAL OLIGOPEPTIDES BY MEANS OF CATALYTIC ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDES
Ojima, Iwao,Yoda, Noriko,Yatabe, Momoko,Tanaka, Toshiyuki,Kogure, Tetsuo
, p. 1255 - 1268 (2007/10/02)
Asymmetric hydrogenation of Ac-ΔTyr(Ac)-(S)-Ala-Gly-OMe (6), Ac-ΔTyr(Ac)-(R)-Ala-Gly-(S)-Phe-OMe (7), Ac-ΔPhe-NH-CH(R)-CH2-OCH2Ph (10), HCO-ΔPhe-(S)-Leu-OMe (16), X-AA-ΔPhe-AA'-OMe ( 5: X=tBOC, CBZ, CF3CO; AA, AA'= α-amino acid ), and t
SYNTHESIS OF ENKEPHALIN ANALOGS VIA ASYMMETRIC HYDROGENATION OF DEHYDROPEPTIDE BUILDING BLOCKS
Ojima, Iwao,Yoda, Noriko,Yatabe, Momoko
, p. 3917 - 3920 (2007/10/02)
1, D-Ala2, Leu5-OMe>Enkephalin and 1, D-Ala2, Leu5-OMe>Enkephalin were succesfully synthesized by the coupling of dipeptide units and tripeptide units which were readily obt
Synthesis of Chiral Dipeptides by means of Asymmetric Hydrogenation of Dehydro Dipeptides
Ojima, Iwao,Kogure, Tetsuo,Yoda, Noriko,Suzuki, Tadashi,Yatabe, Momoko,Tanaka, Toshiyuki
, p. 1329 - 1334 (2007/10/02)
Asymmetric hydrogenation of various dehydro dipeptides was carried out by using rhodium complex catalysts with a variety of chiral diphosphine ligands.The efficiency of chiral diphosphine ligands as well as the effect of the chiral center in the substrate
