7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one

Base Information

Chemical Name:7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one
CAS No.:25526-84-5
Molecular Formula:C₁₄H₁₄O₂
Molecular Weight:214.264
Hs Code.:
NSC Number:152873
DSSTox Substance ID:DTXSID10302709

Synonyms:25526-84-5;NSC 152873;7-methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one;NSC152873;SCHEMBL11684922;DTXSID10302709;NSC-152873

Suppliers and Price of 7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one

Chemical Property:

Vapor Pressure:6.1E-06mmHg at 25°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:214.099379685
Heavy Atom Count:16
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C3=CC(=O)CC3CC2

Technology Process of 7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one

There total 5 articles about 7-Methoxy-3,3a,4,5-tetrahydro-2h-cyclopenta[a]naphthalen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 201230-82-2
carbon monoxide

: 681427-55-4
2-(but-3-enyl)-1-ethynyl4-methoxybenzene

: 25526-84-5
7-methoxyl-3,3a,4,5-tetrahydro-2H-cyclopenta[a]naphthalen-2-one

Guidance literature:: With dicobalt octacarbonyl; In toluene; at 150 ℃; for 0.316667h; under 15001.5 Torr; Flow reactor;
DOI:10.1039/c7cc01749a

Reference yield:

: 27752-23-4
2-Acetonyl-1,2,3,4-tetrahydro-6-methoxy-1-oxo-naphthalin

: 25526-84-5
7-methoxyl-3,3a,4,5-tetrahydro-2H-cyclopenta[a]naphthalen-2-one

Guidance literature:: With sodium hydride; In toluene;
DOI:10.1021/jm00296a043

Reference yield:

: 25591-12-2
Methyl 1,2,3,4-Tetrahydro-6-methoxy-1-oxo-2-(2-propynyl)-2-naphthalene-carboxyl-ate

: 25526-84-5
7-methoxyl-3,3a,4,5-tetrahydro-2H-cyclopenta[a]naphthalen-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: aq. HCO₂H, Hg(OAc)2 / acetic acid

2: aq. KOH / ethanol

3: NaH / toluene

With potassium hydroxide; formic acid; mercury(II) diacetate; sodium hydride; In ethanol; acetic acid; toluene;
DOI:10.1021/jm00296a043