(+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone

Base Information

Chemical Name:(+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone
CAS No.:129885-83-2
Molecular Formula:C₂₈H₂₈O₄
Molecular Weight:428.528
Hs Code.:

Synonyms:

Suppliers and Price of (+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone

There total 28 articles about (+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 694-98-4
norborn-5-en-2-one

: 129885-83-2,144938-76-1
(+/-)-2α,3α-Isopropylidenedioxy-4β-(triphenylmethoxymethyl)cyclopentanone

Guidance literature:: Multi-step reaction with 12 steps

1: 30percent H₂O₂, NaOH / diethyl ether; H₂O / 2 h / Ambient temperature

2: dimethylformamide / 16 h / Ambient temperature

3: pyridine, N,N-dimethylaminopyridine / CH₂Cl₂ / Ambient temperature

4: N-methylmorpholine-N-oxide, OsO₄ / acetone / 16 h / Ambient temperature

5: 71.6 percent / TosOH / 1 h / Ambient temperature

6: 97 percent / LiAlH₄ / diethyl ether / 1) r.t., 15 min, 2) reflux, 15 min

7: 87 percent / Ph₃P, Br, Et₃N / CH₂Cl₂ / 0.25 h / Ambient temperature

8: 1) NaBH₄ / 1) EtOH, 0 deg C, 15 min, 2) EtOH, r.t., 16 h

9: 30percent H₂O₂ / tetrahydrofuran / 16 h / Ambient temperature

10: 1) OsO₄, NaIO₄, 2) LiAlH₄ / 1) Et₂O, H₂O, r.t., 16 h, 2) Et₂O, a) r.t., 15 min, b) reflux, 15 min

11: 78.8 percent / pyridine, N,N-dimethylaminopyridine / CH₂Cl₂ / 4 h / Ambient temperature

12: PDC / CH₂Cl₂ / 16 h / Ambient temperature

With pyridine; dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; dipyridinium dichromate; bromine; dihydrogen peroxide; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)81872-X

Reference yield:

: 129885-79-6
((1R,4R)-4-Acetoxy-cyclopent-2-enyl)-acetic acid methyl ester

: 129885-83-2
(3aR,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-cyclopenta[1,3]dioxol-4-one

Guidance literature:: Multi-step reaction with 5 steps

1: 1) OsO₄, NMNO / 2) p-TsOH / 1) acetone

2: 97 percent / LiAlH₄ / diethyl ether / 0 °C

4: 1) OsO₄, NaIO₄, 2) LiAlH₄ / 1) H₂O/ether, 2) ether

5: 1) DMAP, 2) pyridinium chlorochromate / 1) CH₂Cl₂

With dmap; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; bis-(2-chloro-ethyl)-methyl-amine oxide; pyridinium chlorochromate; toluene-4-sulfonic acid; In diethyl ether;
DOI:10.1016/0040-4039(90)80170-Q

Reference yield:

: 110289-12-8,132312-60-8,137821-17-1,137821-20-6,137821-21-7,138382-24-8,138382-25-9,147332-44-3
(+/-)-(1β,4β)-1-(triphenylmethoxymethyl)cyclopent-2-en-4-ol

: 129885-83-2
(3aR,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-cyclopenta[1,3]dioxol-4-one

Guidance literature:: Multi-step reaction with 5 steps

1: 75 h / Ambient temperature; Pseudomonas fluorescens lipase

2: N-Methylmorpholine N-oxide / osmium tetraoxide / acetone; H₂O; butan-1-ol / 15 h / Ambient temperature

3: p-toluenesulfonic acid

4: sodium methoxide / methanol / 3.5 h

5: pyridinium chlorochromate, 4 Angstroem molecular sieves / CH₂Cl₂ / 1 h / Ambient temperature

With 4 A molecular sieve; sodium methylate; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; pyridinium chlorochromate; osmium(VIII) oxide; In methanol; dichloromethane; water; acetone; butan-1-ol;