Dodec-10-enoic acid

Base Information

• Chemical Name: Dodec-10-enoic acid
• CAS No.: 127818-75-1
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• DSSTox Substance ID: DTXSID50695607
• Wikidata: Q27117687
• Mol file: 127818-75-1.mol

Synonyms:dodec-10-enoic acid;127818-75-1;DTXSID50695607;AZCVFLMXESYPIR-UHFFFAOYSA-N;Q27117687

Chemical Property of Dodec-10-enoic acid

Chemical Property:

• Melting Point: 9.63°C (estimate)
• Refractive Index: 1.4426 (estimate)
• Boiling Point: 321.28°C (estimate)
• PSA: 37.30000
• Density: 0.9176 (rough estimate)
• LogP: 3.76790
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 198.161979940
• Heavy Atom Count: 14
• Complexity: 162

Purity/Quality:

99% ，98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=CCCCCCCCCC(=O)O

Technology Process of Dodec-10-enoic acid

There total 14 articles about Dodec-10-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

dodec-10-(E)-en-1-ol (35237-63-9) → trans-10-dodecenoic acid (148751-11-5,127818-75-1)

Guidance literature:

With dipyridinium dichromate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1016/j.bmc.2004.04.001

Reference yield:

(E)-Dodec-10-enoic acid benzyl ester → trans-10-dodecenoic acid (148751-11-5,127818-75-1) + 11Z-dodecenoic acid (18654-82-5,127818-75-1)

Guidance literature:

With sodium hydroxide; In acetonitrile; at 60 ℃; for 24h; Title compound not separated from byproducts;

DOI:10.1021/jo991338i

Reference yield:

(E)-Dodec-10-enoic acid benzyl ester → trans-10-dodecenoic acid (148751-11-5,127818-75-1) + 11Z-dodecenoic acid (18654-82-5,127818-75-1)

Guidance literature:

With sodium hydroxide; In acetonitrile; at 60 ℃; for 24h; Title compound not separated from byproducts;

DOI:10.1021/jo991338i

upstream raw materials:

1,10-dibromoundecane

potassium cyanide

dodec-10-(E)-en-1-ol

(E)-12-methoxymethoxydodec-2-ene

Refernces

• 1、 Ahmed, Tonia S.,Montgomery, T. Patrick,Grubbs, Robert H.. "Using stereoretention for the synthesis of e -macrocycles with ruthenium-based olefin metathesis catalysts". . p. 3580 - 3583. Retrieved 2018/04/12.