35237-63-9

Basic information

• Product Name: TRANS-10-DODECENOL
• Synonyms: TRANS-10-DODECENOL;(E)-10-Dodecen-1-ol;trans-10-dodecanol;dodec-10-(E)-en-1-ol
• CAS NO: 35237-63-9
• Molecular Formula: C₁₂H₂₄O
• Molecular Weight: 184.31836
• Mol File: 35237-63-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 248.6°C at 760 mmHg
• Flash Point: 105.4°C
• Appearance: /
• Density: 0.846g/cm³
• Vapor Pressure: 0.00387mmHg at 25°C
• Refractive Index: 1.456
• Storage Temp.: 2-8°C
• PKA: 15.20±0.10(Predicted)
• CAS DataBase Reference: TRANS-10-DODECENOL(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-10-DODECENOL(35237-63-9)
• EPA Substance Registry System: TRANS-10-DODECENOL(35237-63-9)

Safety Data

• Hazardous Substances Data: 35237-63-9(Hazardous Substances Data)

Usage

Uses

Dodec-10-en-1-ol can be used in biological study of inhibition of Chlorella growth by degradation and related products of linoleic and linolenic acids and the possible significance of polyunsaturated fatty acids in phytoplankton ecology.

InChI:InChI=1/C12H24O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h2-3,13H,4-12H2,1H3/b3-2+

Upstream product

• 69221-99-4 dodec-10-yn-1-ol 
• 736177-62-1 (E)-12-methoxymethoxydodec-2-ene 
• 86252-56-4 1-(tetrahydropyran-2'-yloxy)-dodec-10-yne 
• 51953-88-9 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne 
• 112-38-9 10-undecenoic acid 
• 2777-65-3 undec-10-ynoic acid 
• 2774-84-7 undec-10-yn-1-ol 
• 175914-87-1 10-(methoxymethoxy)decan-1-ol 
• 112-47-0 1,10-Decanediol 
• 736177-58-5 ethyl (E)-12-methoxymethoxydodec-2-enoate 
• 736177-60-9 (E)-12-methoxymethoxydodec-2-en-1-ol 

Downstream Products

• 35153-09-4 (E)-10-dodecenyl acetate 
• 148751-11-5 trans-10-dodecenoic acid 

Relevant articles and documents

Using stereoretention for the synthesis of e -macrocycles with ruthenium-based olefin metathesis catalysts

The synthesis of E-macrocycles is achieved using stereoretentive, Ru-based olefin metathesis catalysts supported by dithiolate ligands. Kinetic studies elucidate marked differences in activity among the catalysts tested, with catalyst 4 providing meaningful yields of products in much shorter reaction times than stereoretentive catalysts 2 and 3. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high yields (47-80% yield) from diene starting materials bearing two E-configured olefins. A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide.

Structural requirements of dictyopyrones isolated from Dictyostelium spp. in the regulation of Dictyostelium development and in anti-leukemic activity

Cellular slime molds are fascinating to the field of developmental biology, and have long been used as excellent model organisms for the study of various aspects of multicellular development. We have recently isolated α-pyronoids, named dictyopyrones A-D (1-4), from various species of Dictyostelium cellular slime molds, and it was shown that compound 3 may regulate Dictyostelium development. In this study, we synthesized dictyopyrones A-D (1-4) and their analogues, investigated the physiological role of the molecules in cell growth and morphogenesis in D. discoideum, and further verified their effects on human leukemia K562 cells. Nitrogen-containing compounds 22 and 37 strongly inhibited cell growth in K562 leukemia cells, indicating that these compounds may be utilized as novel lead compounds for anti-leukemic agents.