4,5-Diphenyl-3H-1,2-dithiole-3-thione

Base Information

• Chemical Name: 4,5-Diphenyl-3H-1,2-dithiole-3-thione
• CAS No.: 13232-76-3
• Molecular Formula: C15H10 S3
• Molecular Weight: 286.442
• Hs Code.: 2930909090
• Mol file: 13232-76-3.mol

Synonyms:1,2-Dithiole-3-thione,4,5-diphenyl- (6CI); 4,5-Diphenyl-1,2-dithiole-3-thione; NSC 149665

Chemical Property of 4,5-Diphenyl-3H-1,2-dithiole-3-thione

Chemical Property:

• Vapor Pressure: 3.98E-08mmHg at 25°C
• Boiling Point: 457.7°C at 760 mmHg
• Flash Point: 230.6°C
• PSA: 88.57000
• Density: 1.38g/cm³
• LogP: 5.87310

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5-Diphenyl-3H-1,2-dithiole-3-thione

There total 31 articles about 4,5-Diphenyl-3H-1,2-dithiole-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3,4-Diphenyl-1,2-dithiolylium-bromid (55836-89-0) → 4,5-diphenyl-[1,2]dithiole-3-thione (13232-76-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 1h;

Reference yield: 84.0%

2,3-diphenylcyclopropen-1-thione (2570-01-6) → 4,5-diphenyl-[1,2]dithiole-3-thione (13232-76-3)

Guidance literature:

With sulfur; potassium fluoride; In N,N-dimethyl-formamide; at 20 ℃; for 12h; regioselective reaction; Schlenk technique;

DOI:10.1021/acs.orglett.0c01914

Reference yield: 83.0%

2-[4-(2-Oxo-1,2-diphenyl-ethylidene)-[1,3]dithietan-2-ylidene]-1,2-diphenyl-ethanone (19018-13-4,32279-75-7,32279-85-9) → 4,5-diphenyl-[1,2]dithiole-3-thione (13232-76-3)

Guidance literature:

With tetraphosphorus decasulfide; In pyridine; for 24h; Heating;

upstream raw materials:

(E)-1,2-diphenylpropene

1,2-diphenylpropan-1-one

4-cyclohexen-1-ylmorpholine

4,5-Diphenyl-3H-1,2-dithiol-3-thion-S-oxid

Downstream raw materials:

2,3,5,6-tetraphenylthieno[3,2-b]thiophene

triphenylphosphine sulfide

diphenyl acetylene

chlorure de chloro-3 diphenyl-4,5 dithiole-1,2 ylium

Refernces

• 1、 Bai, Feifei,Fang, Jianguo,Song, Zi-Long,Zhang, Baoxin. "Synthesis of Dithiolethiones and Identification of Potential Neuroprotective Agents via Activation of Nrf2-Driven Antioxidant Enzymes". . p. 2214 - 2231. Retrieved 2020/03/06.
• 2、 Amzil, Jamal,Catel, Jean-Marie,Le Coustumer, Gerard,Mollier, Yves,Sauve, Jean-Pierre. "Syntheses de bis(dithiole-1,2 et diselenole-1,2 ylidenes)-3,3' et de derives du dithietanne-1,3". . p. 101 - 105. Retrieved 2007/10/02.