1-Benzyl-1,7-diazaspiro[4.4]nonane

Base Information

Chemical Name:1-Benzyl-1,7-diazaspiro[4.4]nonane
CAS No.:128244-01-9
Molecular Formula:C14H20N2
Molecular Weight:216.326
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20576070
Mol file:128244-01-9.mol

Synonyms:1-benzyl-1,7-diazaspiro[4.4]nonane;128244-01-9;1,7-DIAZASPIRO[4.4]NONANE, 1-(PHENYLMETHYL)-;1-Benzyl-1,7-diaza-spiro[4.4]nonane;1-benzyl-1,7-diazaspiro[4,4]nonane;MFCD09056754;SCHEMBL1556809;DTXSID20576070;YIZAKHJUGTXWTG-UHFFFAOYSA-N;AKOS022689937;MB06923;1-Benzyl-1,7-diazaspiro[4.4] nonane;AS-31988;SY026889;EN300-79274;1-Benzyl-1 pound not7-diazaspiro[4.4]nonane;A889051;Z1210306980

Suppliers and Price of 1-Benzyl-1,7-diazaspiro[4.4]nonane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Benzyl-1,7-Diazaspiro[4.4]Nonane
50mg
$ 110.00

Frontier Specialty Chemicals
1-Benzyl-1,7-diazaspiro[4.4]nonanehemioxalate 95%
100mg
$ 274.00

Crysdot
1-Benzyl-1,7-diazaspiro[4.4]nonane 95+%
1g
$ 550.00

Chemenu
1-Benzyl-1,7-diazaspiro[4.4]nonane 95%
1g
$ 311.00

Chemenu
1-Benzyl-1,7-diazaspiro[4.4]nonane 95%
5g
$ 844.00

American Custom Chemicals Corporation
1-BENZYL-1,7-DIAZA-SPIRO[4.4]NONANE 95.00%
1G
$ 1070.84

American Custom Chemicals Corporation
1-BENZYL-1,7-DIAZA-SPIRO[4.4]NONANE 95.00%
5G
$ 2181.31

American Custom Chemicals Corporation
1-BENZYL-1,7-DIAZA-SPIRO[4.4]NONANE 95.00%
2.5G
$ 1635.30

Alichem
1-Benzyl-1,7-diazaspiro[4.4]nonane
5g
$ 1285.20

Alichem
1-Benzyl-1,7-diazaspiro[4.4]nonane
1g
$ 424.32

Total 9 raw suppliers

Chemical Property of 1-Benzyl-1,7-diazaspiro[4.4]nonane

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:328.073oC at 760 mmHg
PKA:10.68±0.20(Predicted)
Flash Point:135.18oC
PSA：15.27000
Density:1.089g/cm3
LogP:2.28120
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:216.162648646
Heavy Atom Count:16
Complexity:235

Purity/Quality:

98% ^*data from raw suppliers

1-Benzyl-1,7-Diazaspiro[4.4]Nonane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCNC2)N(C1)CC3=CC=CC=C3

Technology Process of 1-Benzyl-1,7-diazaspiro[4.4]nonane

There total 7 articles about 1-Benzyl-1,7-diazaspiro[4.4]nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

: 646055-59-6
6-benzyl-2,6-diazaspiro[4.4]nonan-1-one

: 128244-01-9
1-(phenylmethyl)-1,7-diazaspiro<4.4>nonane

Guidance literature:: 6-benzyl-2,6-diazaspiro[4.4]nonan-1-one; With lithium aluminium tetrahydride; In tetrahydrofuran; for 24h; Heating / reflux;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 1h;

Reference yield: 95.6%

: 128244-00-8
1-benzoyl-1,7-diazaspiro<4.4>nonan-6-one

: 128244-01-9
1-(phenylmethyl)-1,7-diazaspiro<4.4>nonane

Guidance literature:: 1-benzoyl-1,7-diazaspiro<4.4>nonan-6-one; With lithium aluminium tetrahydride; In tetrahydrofuran; at 10 ℃; for 21.85h; Inert atmosphere; Reflux;

With water; sodium hydroxide; In tetrahydrofuran; Cooling with ice-water;

Reference yield:

: 128243-98-1
methyl 1-benzoyl-2-(nitrilomethyl)pyrrolidine-2-carboxylate

: 128244-01-9
1-(phenylmethyl)-1,7-diazaspiro<4.4>nonane

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Raney nickel / methanol; tetrahydrofuran / 46 h / 50 °C / 2585.7 Torr

2: toluene / 48 h / Heating

3: lithium aluminum hydride / tetrahydrofuran / 1.) RT, 2 d, 2.) reflux, 2 h

With lithium aluminium tetrahydride; hydrogen; nickel; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/jm00170a035