128244-00-8 Usage
General Description
1,7-DIAZASPIRO[4.4]NONAN-6-ONE, 1-BENZOYL is a chemical compound with the molecular formula C16H14N2O2. It is a derivative of 1,7-diazaspiro[4.4]nonan-6-one and contains a benzoate group. 1,7-DIAZASPRIO[4.4]NONAN-6-ONE, 1-BENZOYL has been investigated for its pharmaceutical potential, particularly as an antipsychotic agent. It has shown activity as a potent and selective dopamine D3 receptor antagonist, with potential applications in the treatment of disorders such as schizophrenia. Additionally, 1,7-DIAZASPIRO[4.4]NONAN-6-ONE, 1-BENZOYL has been studied for its potential as a psychoactive substance and for its effects on other neurotransmitter systems. Overall, this compound has generated interest for its potential therapeutic applications and its pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 128244-00-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,2,4 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 128244-00:
(8*1)+(7*2)+(6*8)+(5*2)+(4*4)+(3*4)+(2*0)+(1*0)=108
108 % 10 = 8
So 128244-00-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H16N2O2/c17-12(11-5-2-1-3-6-11)16-10-4-7-14(16)8-9-15-13(14)18/h1-3,5-6H,4,7-10H2,(H,15,18)
128244-00-8Relevant articles and documents
SUBSTITUTED 2-HYDROGEN-PYRAZOLE DERIVATIVE SERVING AS ANTICANCER DRUG
-
, (2018/02/04)
Disclosed is a substituted 2H-pyrazole derivative serving as a selective CDK4/6 inhibitor. Specifically, disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof which serves as a selective CDK4/6 inhibitor.
Quinolone Antibacterial Agents Substituted at the 7-Position with Spiroamines. Synthesis and Structure-Activity Relationships
Culbertson, Townley P.,Sanchez, Joseph P.,Gambino, Laura,Sesnie, Josephine A.
, p. 2270 - 2275 (2007/10/02)
A series of fluoroquinolone antibacterials having the 7-position (10-position of pyridobenzoxazines) substituted with 2,7-diazaspirononane (4b), 1,7-diazaspirononane (5a), or 2,8-diazaspiroundecane (6b) was prepared, and their biological activities were compared with piperazine and pyrrolidine substituted analogues.Most exhibited potent Gram-positive and Gram-negative activity, especially when side chain 4b was N-alkylated.