4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline

Base Information

Chemical Name:4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline
CAS No.:128256-23-5
Molecular Formula:C21H15N3O2
Molecular Weight:341.36300
Hs Code.:
Mol file:128256-23-5.mol

Synonyms:6-methyl-4-(4-nitrophenyl)-2-phenylquinazoline;6-Methyl-4-(4-nitro-phenyl)-2-phenyl-quinazoline;

Suppliers and Price of 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline

Chemical Property:

PSA：71.60000
LogP:5.70360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline

There total 3 articles about 4-{4-nitrophenyl}-6-methyl-2-phenylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1859-00-3
(Z)-N'-(4-methylphenyl)benzamidine

: 555-16-8
4-nitrobenzaldehdye

: 128256-23-5
6-methyl-4-(4'-nitrophenyl)-2-phenylquinazoline

Guidance literature:: microwave irradiation;
DOI:10.1016/j.tet.2005.01.118

Reference yield: 73.0%

: 71316-14-8
N'-(4-methylphenyl)-N-(triphenylphosphoranylidene)-benzenecarboximidamide

: 555-16-8
4-nitrobenzaldehdye

: 128256-23-5
6-methyl-4-(4'-nitrophenyl)-2-phenylquinazoline

Guidance literature:: for 0.0666667h; microwave irradiation;
DOI:10.1081/SCC-120027237

Reference yield:

: 66275-61-4
N-Chloro-N'-(4-methylphenyl)benzamidine

: 128256-23-5
6-methyl-4-(4'-nitrophenyl)-2-phenylquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 2) 2M NaOH / 1) CH₂Cl₂, -50 deg C, 10 min

2: 70 percent / xylene / 12 h / Heating

With sodium hydroxide; In xylene;
DOI:10.1016/S0040-4039(00)94659-8