4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid

Base Information

Chemical Name:4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid
CAS No.:128537-48-4
Molecular Formula:C7H9BrN2O2
Molecular Weight:233.06300
Hs Code.:2933199090
DSSTox Substance ID:DTXSID90564101
Wikidata:Q82448688
Mol file:128537-48-4.mol

Synonyms:128537-48-4;4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid;1H-Pyrazole-5-carboxylic acid, 4-bromo-3-ethyl-1-methyl-;4-BROMO-5-ETHYL-2-METHYLPYRAZOLE-3-CARBOXYLIC ACID;4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylicacid;SCHEMBL6819929;DTXSID90564101;MFCD08459058;AKOS017558614;AS-70144;W16047;A805834;4-bromo-5-ethyl-2-methyl-pyrazole-3-carboxylic acid

Suppliers and Price of 4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-BROMO-3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 95.00%
5MG
$ 496.35

Total 9 raw suppliers

Chemical Property of 4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid

Chemical Property:

PSA：55.12000
LogP:1.44320
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.98474
Heavy Atom Count:12
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

4-BROMO-3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NN(C(=C1Br)C(=O)O)C

Technology Process of 4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid

There total 5 articles about 4-Bromo-3-ethyl-1-methyl-1H-pyrazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 128537-28-0
ethyl 1-methyl-3-ethyl-4-bromine-1Hpyrazole-5-carboxylate

: 128537-48-4
C₇H₉BrN₂O₂

Guidance literature:: ethyl 1-methyl-3-ethyl-4-bromine-1Hpyrazole-5-carboxylate; With water; sodium hydroxide; In methanol; for 4h; Reflux;

In methanol; pH=2; Acidic conditions;
DOI:10.1016/j.cclet.2012.04.010

Reference yield:

: 1354829-67-6
C₈H₁₁BrN₂O₂

: 128537-48-4
C₇H₉BrN₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 10 h / 50 °C

2.1: water; sodium hydroxide / methanol / 4 h / Reflux

2.2: pH 2 / Acidic conditions

With water; potassium carbonate; sodium hydroxide; In methanol; acetone;
DOI:10.1016/j.cclet.2012.04.010

Reference yield:

: 26308-40-7
ethyl 3-ethyl-1H-pyrazole-5-carboxylate

: 128537-48-4
C₇H₉BrN₂O₂

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / chloroform / 12 h / 20 °C

2.1: potassium carbonate / acetone / 10 h / 50 °C

3.1: water; sodium hydroxide / methanol / 4 h / Reflux

3.2: pH 2 / Acidic conditions

With N-Bromosuccinimide; water; potassium carbonate; sodium hydroxide; In methanol; chloroform; acetone;
DOI:10.1016/j.cclet.2012.04.010