Technology Process of C24H20FN3O4
There total 3 articles about C24H20FN3O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 4 h / 90 °C / Inert atmosphere
2: caesium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
3: lithium hydroxide; water / tetrahydrofuran / 16 h / 70 °C
With
palladium bis[bis(diphenylphosphino)ferrocene] dichloride; water; potassium carbonate; caesium carbonate; lithium hydroxide;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;
1: |Suzuki Coupling;
DOI:10.1021/ml400192w
- Guidance literature:
-
Multi-step reaction with 2 steps
1: caesium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
2: lithium hydroxide; water / tetrahydrofuran / 16 h / 70 °C
With
water; caesium carbonate; lithium hydroxide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ml400192w
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-iodo-succinimide / acetone / 3 h / 20 °C
2: palladium bis[bis(diphenylphosphino)ferrocene] dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 4 h / 90 °C / Inert atmosphere
3: caesium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C
4: lithium hydroxide; water / tetrahydrofuran / 16 h / 70 °C
With
N-iodo-succinimide; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; water; potassium carbonate; caesium carbonate; lithium hydroxide;
In
tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; acetone;
2: |Suzuki Coupling;
DOI:10.1021/ml400192w
