L-3,3'-Diiodothyronine

Base Information

• Chemical Name: L-3,3'-Diiodothyronine
• CAS No.: 58342-32-8
• Molecular Formula: C₁₅H₁₃I₂NO₄
• Molecular Weight: 525.082
• Mol file: 58342-32-8.mol

Synonyms:

Chemical Property of L-3,3'-Diiodothyronine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-3,3'-Diiodothyronine

There total 15 articles about L-3,3'-Diiodothyronine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triiodothyronine (6893-02-3,15785-49-6,7013-53-8) → L-3,3'-Diiodothyronine (70-40-6,58342-32-8,4604-41-5)

Guidance literature:

With Naphthalene-1,8-diselenol; D,L-dithiothreitol; at 37 ℃; pH=7.5; pH-value; Concentration; Time; Reagent/catalyst; regioselective reaction; Kinetics; aq. phosphate buffer;

DOI:10.1021/ja201657s

Reference yield:

triiodothyronine (6893-02-3,15785-49-6,7013-53-8) → 3'-Iodothyronine (4732-82-5) + 3-Monoiodothyronine (10468-90-3) + L-3,3'-Diiodothyronine (70-40-6,58342-32-8,4604-41-5) + O-(4-hydroxyphenyl)-3,5-diiodo-L-tyrosine (1596-67-4)

Guidance literature:

With sodium tetrahydroborate; C₁₀H₈STe; D,L-dithiothreitol; In aq. phosphate buffer; at 37 ℃; for 0.5h; pH=7.5; Reagent/catalyst; regioselective reaction;

DOI:10.1002/anie.201502762

Reference yield:

L-3,3',5'-triiodothyronine (5817-39-0) → 3'-Iodothyronine (4732-82-5) + 3-Monoiodothyronine (10468-90-3) + L-3,3'-Diiodothyronine (70-40-6,58342-32-8,4604-41-5) + 3',5'-Diiodothyronine (4192-14-7)

Guidance literature:

With sodium tetrahydroborate; C₁₀H₈Te₂; D,L-dithiothreitol; In aq. phosphate buffer; at 37 ℃; for 0.5h; pH=7.5; regioselective reaction;

DOI:10.1002/anie.201502762

upstream raw materials:

3-Monoiodothyronine

N-acetyl-3-iodo-L-tyrosine

(S)-2-Acetylamino-3-[3-iodo-4-(4-methoxy-phenoxy)-phenyl]-propionamide

N-Acetyl-3-iodo-L-tyrosinamid

Downstream raw materials:

3'-Iodothyronine

3-Monoiodothyronine

O-(4-hydroxyphenyl)-3,5-diiodo-L-tyrosine

3,3'-diiodo-L-thyronine sulfate