O^1,4-(β-D-Galactopyranosyl)-4>-morphiceptin

Base Information

• Chemical Name: O^1,4-(β-D-Galactopyranosyl)-4>-morphiceptin
• CAS No.: 125281-19-8
• Molecular Formula: C₃₄H₄₅N₅O₁₁
• Molecular Weight: 699.758
• Mol file: 125281-19-8.mol

Synonyms:

Chemical Property of O^1,4-(β-D-Galactopyranosyl)-4>-morphiceptin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O^1,4-(β-D-Galactopyranosyl)-4>-morphiceptin

There total 4 articles about O^1,4-(β-D-Galactopyranosyl)-4>-morphiceptin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-4-((2R,3R,4S,5S,6R)-3,4,5-Triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester (125281-20-1,125355-37-5,125355-40-0,125355-41-1) → O1,4-(β-D-Galactopyranosyl)-4>-morphiceptin (125281-19-8,125355-36-4,125355-38-6,125355-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC / CH₂Cl₂

2: solid phase peptide synthesis

With dicyclohexyl-carbodiimide; In dichloromethane;

Reference yield:

(S)-4-((2R,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester (125281-20-1,125355-37-5,125355-40-0,125355-41-1) → O1,4-(β-D-Glucopyranosyl)-4>-morphiceptin (125281-19-8,125355-36-4,125355-38-6,125355-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC / CH₂Cl₂

2: solid phase peptide synthesis

With dicyclohexyl-carbodiimide; In dichloromethane;

Reference yield:

N-Fmoc-Tyr-OH (112883-29-1,92954-90-0) + (S)-4-((2R,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 2-benzotriazol-1-yl ester 1-(9H-fluoren-9-ylmethyl) ester + Fmoc-Pro-OH (71989-31-6) + N-Fmoc L-Phe (35661-40-6) → O1,4-(β-D-Glucopyranosyl)-4>-morphiceptin (125281-19-8,125355-36-4,125355-38-6,125355-39-7)

Guidance literature:

Yield given. Multistep reaction; solid phase peptide synthesis;

upstream raw materials:

N-Fmoc-Tyr-OH

Fmoc-Pro-OH

N-Fmoc L-Phe

(S)-4-((2R,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester