C₂₀H₂₄N₂O₆

Base Information

• Chemical Name: C₂₀H₂₄N₂O₆
• CAS No.: 1351822-75-7
• Molecular Formula: C₂₀H₂₄N₂O₆
• Molecular Weight: 388.42
• Mol file: 1351822-75-7.mol

Synonyms:

Chemical Property of C₂₀H₂₄N₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₄N₂O₆

There total 1 articles about C₂₀H₂₄N₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

terephthalonitrile (623-26-7) + acetic anhydride (108-24-7) + ethyl bromoacetate (105-36-2) → ethyl 2-(amino(4-cyanophenyl)methylene)-3-oxobutanoate (1351822-74-6) + C20H24N2O6 (1351822-75-7)

Guidance literature:

terephthalonitrile; ethyl bromoacetate; With zinc; In tetrahydrofuran; for 1h; Reflux;

With n-butyllithium; at 0 ℃;

acetic anhydride; at 20 ℃; for 3h;

DOI:10.1055/s-0030-1260304

Reference yield: 36.0%

pyridine-2-carbonyl chloride (29745-44-6) + C20H24N2O6 (1351822-75-7) → C32H30N4O8 (1351822-82-6)

Guidance literature:

With triethylamine; In 1,2-dichloro-ethane; for 24h; Reflux;

DOI:10.1055/s-0030-1260304

Reference yield:

C20H24N2O6 (1351822-75-7) → C40H24F18N4O10S2 (1351822-90-6)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / 1,2-dichloro-ethane / 24 h / Reflux

2: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 120 h / 90 °C

3: sodium hydride / tetrahydrofuran / 20 °C

With trimethylsilyl trifluoromethanesulfonate; sodium hydride; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1055/s-0030-1260304

upstream raw materials:

terephthalonitrile

acetic anhydride

ethyl bromoacetate

Downstream raw materials:

C₃₂H₃₀N₄O₈

C₄₀H₂₄F₁₈N₄O₁₀S₂