4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone

Base Information

Chemical Name:4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone
CAS No.:86232-29-3
Molecular Formula:C₁₂H₁₅ClO₄
Molecular Weight:258.702
Hs Code.:
DSSTox Substance ID:DTXSID501214665

Synonyms:86232-29-3;4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone;DTXSID501214665

Suppliers and Price of 4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:258.0658866
Heavy Atom Count:17
Complexity:259

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)CC(C1=C(C(=CC(=C1)Cl)OC)OC)O

Technology Process of 4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone

There total 4 articles about 4-(5-Chloro-2,3-dimethoxyphenyl)-4-hydroxy-2-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 86232-26-0
3-methoxy-2-hydroxy-5-chlorotoluene

: 67-64-1
acetone

: 77-78-1
dimethyl sulfate

: 86232-28-2
5-chloro-2,3-dimethoxybenzaldehyde

: 86232-29-3
4-(2,3-dimethoxy-5-chlorophenyl)-4-hydroxy-2-butanone

Guidance literature:: With potassium carbonate; In acetone; for 5h; Heating;

Reference yield: 11.0%

: 86232-26-0
3-methoxy-2-hydroxy-5-chlorotoluene

: 77-78-1
dimethyl sulfate

: 86232-28-2
5-chloro-2,3-dimethoxybenzaldehyde

: 86232-29-3
4-(2,3-dimethoxy-5-chlorophenyl)-4-hydroxy-2-butanone

Guidance literature:: With potassium carbonate; In acetone; for 5h; Heating;

Reference yield:

: 7740-05-8
5-chloro-2-hydroxy-3-methoxy-benzaldehyde

: 86232-29-3
4-(2,3-dimethoxy-5-chlorophenyl)-4-hydroxy-2-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1) 99percent hydrazine hydrate, 2) KOH / 1) reflux, 5 h, 2) reflux, 5 h

2: 11 percent / K₂CO₃ / acetone / 5 h / Heating

With potassium hydroxide; potassium carbonate; hydrazine hydrate; In acetone;