1,2-Diethyl-3,4-bis(methylene)cyclobutene

Base Information

• Chemical Name: 1,2-Diethyl-3,4-bis(methylene)cyclobutene
• CAS No.: 19686-80-7
• Molecular Formula: C₁₀H₁₄
• Molecular Weight: 134.221
• DSSTox Substance ID: DTXSID001271531
• Mol file: 19686-80-7.mol

Synonyms:1,2-Diethyl-3,4-bis(methylene)cyclobutene;DTXSID001271531;19686-80-7

Chemical Property of 1,2-Diethyl-3,4-bis(methylene)cyclobutene

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 134.109550447
• Heavy Atom Count: 10
• Complexity: 192

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=C(C(=C)C1=C)CC

Technology Process of 1,2-Diethyl-3,4-bis(methylene)cyclobutene

There total 3 articles about 1,2-Diethyl-3,4-bis(methylene)cyclobutene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Deca-3,7-diin (33840-20-9) → Diethyl-dimethylen-cyclobuten (19686-80-7)

Guidance literature:

at 490 ℃;

DOI:10.1016/S0040-4020(01)98256-0

Reference yield:

Ethyl-methyl-dimethylen-cyclobuten (19686-82-9) + methyl iodide (74-88-4) → Diethyl-dimethylen-cyclobuten (19686-80-7)

Guidance literature:

Multistep reaction; (i) nBuLi, (ii) /BRN= 969135/;

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + 1,2-dimethyl-3,4-dimethylidenecyclobutene (25467-12-3) + methyl iodide (74-88-4) → Ethyl-methyl-dimethylen-cyclobuten (19686-82-9) + Diethyl-dimethylen-cyclobuten (19686-80-7) + 1-Ethyl-2-eth-(Z)-ylidene-3,4-dimethylene-cyclobutane (118762-58-6) + 1-Methyl-3,4-dimethylene-2-pentyl-cyclobutene (118762-57-5) + C18H22 (118762-60-0)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; In hexane; for 24h; Product distribution; other quenching agent, var. reaction times;

DOI:10.1021/jo00265a012

upstream raw materials:

Deca-3,7-diin

Ethyl-methyl-dimethylen-cyclobuten

methyl iodide

n-butyllithium