isopropoxyacetic anhydride

Base Information

• Chemical Name: isopropoxyacetic anhydride
• CAS No.: 25769-60-2
• Molecular Formula: C10H18 O5
• Molecular Weight: 218.25
• Hs Code.: 2918990090
• Mol file: 25769-60-2.mol

Synonyms:Acetic acid,(1-methylethoxy)-, anhydride (9CI); Acetic acid, isopropoxy-, anhydride (8CI);Isopropoxyacetic anhydride

Chemical Property of isopropoxyacetic anhydride

Chemical Property:

• Vapor Pressure: 0.0234mmHg at 25°C
• Boiling Point: 249°Cat760mmHg
• Flash Point: 100.6°C
• PSA: 61.83000
• Density: 1.05g/cm³
• LogP: 0.90620

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of isopropoxyacetic anhydride

There total 1 articles about isopropoxyacetic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-isopropoxyacetic acid (33445-07-7) → Isopropyloxyessigsaeure-anhydrid (25769-60-2)

Guidance literature:

With acetic anhydride;

Reference yield: 35.0%

Isopropyloxyessigsaeure-anhydrid (25769-60-2) + p-tolylsulfinyl amide (6873-55-8) → N-isopropoxyacetyl-p-toluenesulfinamide

Guidance literature:

p-tolylsulfinyl amide; With n-butyllithium; In tetrahydrofuran;

Isopropyloxyessigsaeure-anhydrid; In tetrahydrofuran;

DOI:10.1021/ja045397b

Reference yield:

Isopropyloxyessigsaeure-anhydrid (25769-60-2) → (S)-N-isopropoxyacetyl-p-toluenesulfinamide

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran

1.2: 35 percent / tetrahydrofuran

2.1: recombinant subtilisin E / H₂O; various solvent(s) / 24 h / 37 °C / pH 8.0

With n-butyllithium; recombinant subtilisin E; In tetrahydrofuran; water;

DOI:10.1021/ja045397b

upstream raw materials:

2-isopropoxyacetic acid