2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Base Information

Chemical Name:2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane
CAS No.:1618093-00-7
Molecular Formula:C₂₂H₃₅BrO₄
Molecular Weight:443.421
Hs Code.:

Synonyms:

Suppliers and Price of 2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

There total 11 articles about 2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1618092-99-1
[4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxyphenyl]methanol

: 1618093-00-7
2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 0 ℃; Inert atmosphere;
DOI:10.1021/jo501266g

Reference yield:

: 123-31-9,8027-02-9
hydroquinone

: 1618093-00-7
2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Guidance literature:: Multi-step reaction with 10 steps

1.1: potassium hydroxide / dimethyl sulfoxide / 50 °C / Inert atmosphere

2.1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

3.1: potassium acetate; bromine / acetic acid / 50 °C / Inert atmosphere

4.1: sodium hydroxide; water / tert-butyl alcohol / Inert atmosphere; Reflux

5.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux

6.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Dean-Stark; Reflux

7.1: potassium hydroxide / dimethyl sulfoxide / 40 °C / Inert atmosphere

8.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Glovebox; Inert atmosphere

8.2: -78 - 20 °C / Inert atmosphere

9.1: sodium tetrahydroborate / tetrahydrofuran / 0 °C / Inert atmosphere

10.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 °C / Inert atmosphere

With sodium tetrahydroborate; n-butyllithium; carbon tetrabromide; water; bromine; potassium acetate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; potassium hydroxide; sodium hydroxide; magnesium chloride; In tetrahydrofuran; hexane; acetic acid; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol; 1.1: |Williamson Ether Synthesis;
DOI:10.1021/jo501266g

Reference yield:

: 35107-98-3
4-((2-ethylhexyl)oxy)phenol

: 1618093-00-7
2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

Guidance literature:: Multi-step reaction with 9 steps

1.1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2.1: potassium acetate; bromine / acetic acid / 50 °C / Inert atmosphere

3.1: sodium hydroxide; water / tert-butyl alcohol / Inert atmosphere; Reflux

4.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux

5.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Dean-Stark; Reflux

6.1: potassium hydroxide / dimethyl sulfoxide / 40 °C / Inert atmosphere

7.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Glovebox; Inert atmosphere

7.2: -78 - 20 °C / Inert atmosphere

8.1: sodium tetrahydroborate / tetrahydrofuran / 0 °C / Inert atmosphere

9.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 °C / Inert atmosphere

With sodium tetrahydroborate; n-butyllithium; carbon tetrabromide; water; bromine; potassium acetate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; potassium hydroxide; sodium hydroxide; magnesium chloride; In tetrahydrofuran; hexane; acetic acid; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/jo501266g