diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Base Information

Chemical Name:diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate
CAS No.:1618093-01-8
Molecular Formula:C₂₆H₄₅O₇P
Molecular Weight:500.613
Hs Code.:

Synonyms:

Suppliers and Price of diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

There total 12 articles about diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.2%

: 1618093-00-7
2-[4-bromomethyl-5-((2-ethylhexyl)oxy)-2-methoxyphenyl]-5,5-dimethyl-1,3-dioxane

: 122-52-1
triethyl phosphite

: 1618093-01-8
diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Guidance literature:: at 140 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jo501266g

Reference yield:

: 123-31-9,8027-02-9
hydroquinone

: 1618093-01-8
diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Guidance literature:: Multi-step reaction with 11 steps

1.1: potassium hydroxide / dimethyl sulfoxide / 50 °C / Inert atmosphere

2.1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

3.1: potassium acetate; bromine / acetic acid / 50 °C / Inert atmosphere

4.1: sodium hydroxide; water / tert-butyl alcohol / Inert atmosphere; Reflux

5.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux

6.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Dean-Stark; Reflux

7.1: potassium hydroxide / dimethyl sulfoxide / 40 °C / Inert atmosphere

8.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Glovebox; Inert atmosphere

8.2: -78 - 20 °C / Inert atmosphere

9.1: sodium tetrahydroborate / tetrahydrofuran / 0 °C / Inert atmosphere

10.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 °C / Inert atmosphere

11.1: 2 h / 140 °C / Inert atmosphere

With sodium tetrahydroborate; n-butyllithium; carbon tetrabromide; water; bromine; potassium acetate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; potassium hydroxide; sodium hydroxide; magnesium chloride; In tetrahydrofuran; hexane; acetic acid; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol; 1.1: |Williamson Ether Synthesis;
DOI:10.1021/jo501266g

Reference yield:

: 35107-98-3
4-((2-ethylhexyl)oxy)phenol

: 1618093-01-8
diethyl 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2-((2-ethylhexyl)oxy)-5-methoxybenzylphosphonate

Guidance literature:: Multi-step reaction with 10 steps

1.1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2.1: potassium acetate; bromine / acetic acid / 50 °C / Inert atmosphere

3.1: sodium hydroxide; water / tert-butyl alcohol / Inert atmosphere; Reflux

4.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux

5.1: toluene-4-sulfonic acid / toluene / Inert atmosphere; Dean-Stark; Reflux

6.1: potassium hydroxide / dimethyl sulfoxide / 40 °C / Inert atmosphere

7.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Glovebox; Inert atmosphere

7.2: -78 - 20 °C / Inert atmosphere

8.1: sodium tetrahydroborate / tetrahydrofuran / 0 °C / Inert atmosphere

9.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 °C / Inert atmosphere

10.1: 2 h / 140 °C / Inert atmosphere

With sodium tetrahydroborate; n-butyllithium; carbon tetrabromide; water; bromine; potassium acetate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; potassium hydroxide; sodium hydroxide; magnesium chloride; In tetrahydrofuran; hexane; acetic acid; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/jo501266g