Ethyl Piperazine-2-carboxylate Dihydrochloride

Base Information

• Chemical Name: Ethyl Piperazine-2-carboxylate Dihydrochloride
• CAS No.: 129798-91-0
• Molecular Formula: C₇H₁₄N₂O₂*(x)ClH
• Molecular Weight: 231.12014
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID10460196
• Mol file: 129798-91-0.mol

Synonyms:Ethyl Piperazine-2-carboxylate Dihydrochloride;129798-91-0;2-Piperazinecarboxylic acid, ethyl ester, dihydrochloride;ethyl piperazine-2-carboxylate;dihydrochloride;Ethyl piperazine-2-carboxylate diHCl;2-Piperazinecarboxylic acid, ethyl ester, hydrochloride (1:2);ETHYL PIPERAZINE-2-CARBOXYLATE 2HCL;SCHEMBL4283062;DTXSID10460196;XUILSFCCCIHPIE-UHFFFAOYSA-N;AMY35269;MFCD22381964;AKOS015998691;DS-1819;SB40691;2-piperazinecarboxylic acid ethyl ester 2HCl;F1904-0061

Chemical Property of Ethyl Piperazine-2-carboxylate Dihydrochloride

Chemical Property:

• PSA: 50.36000
• LogP: 1.37250
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 230.0588831
• Heavy Atom Count: 13
• Complexity: 138

Purity/Quality:

97% ^*data from raw suppliers

Ethylpiperazine-2-carboxylatedihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1CNCCN1.Cl.Cl

Technology Process of Ethyl Piperazine-2-carboxylate Dihydrochloride

There total 6 articles about Ethyl Piperazine-2-carboxylate Dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 1,4-bis(phenylmethyl)-2-piperazine carboxylate dihydrochloride → ethyl piperazine-2-carboxylate dihydrochloride (129798-91-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; for 16h; under 2585.81 Torr;

Reference yield: 97.0%

ethyl 1,4-dibenzylpiperazin-2-carboxylate (72351-59-8) → ethyl piperazine-2-carboxylate dihydrochloride (129798-91-0)

Guidance literature:

With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; water; at 25 ℃; for 12h;

Reference yield:

N,N'-di-tert-butyloxycarbonylpiperazine-2-carboxylic acid ethyl ester → ethyl piperazine-2-carboxylate hydrochloride (129798-91-0)

Guidance literature:

With hydrogenchloride; In methanol; ethyl acetate; at 20 ℃;

upstream raw materials:

ethyl 1,4-dibenzylpiperazin-2-carboxylate