2-methoxy-1-(methylsulfinyl)-4-nitrobenzene

Base Information

• Chemical Name: 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene
• CAS No.: 861339-82-4
• Molecular Formula: C₈H₉NO₄S
• Molecular Weight: 215.23
• Mol file: 861339-82-4.mol

Synonyms:

Chemical Property of 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene

There total 5 articles about 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl sulfoxide (67-68-5,8070-53-9) + 2-methoxy-4-nitrophenylamine (97-52-9) → 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene (861339-82-4)

Guidance literature:

2-methoxy-4-nitrophenylamine; With tetrafluoroboric acid; sodium nitrite; In water; at 0 ℃; for 0.75h;

dimethyl sulfoxide; With tris(2,2'-bipyridyl)ruthenium dichloride; at 25 ℃; for 2.5h; Irradiation; Inert atmosphere;

DOI:10.1039/c6cc04142f

Reference yield:

(2-methoxy-4-nitrophenyl)(methyl)sulfane (4163-77-3) → 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene (861339-82-4)

Guidance literature:

With nitric acid; at 0 ℃;

Reference yield:

2-chloro-5-nitroanisole (1009-36-5) → 2-methoxy-1-(methylsulfinyl)-4-nitrobenzene (861339-82-4)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous-alcoholic sodium sulfide

2: aqueous NaOH-solution

3: fuming nitric acid / 0 °C

With sodium sulfide; sodium hydroxide; nitric acid;

upstream raw materials:

(2-methoxy-4-nitrophenyl)(methyl)sulfane

nitric acid

2-chloro-5-nitroanisole

2-methoxy-4-nitrobenzenethiol

Downstream raw materials:

2-methoxy-1-(methylsulfonyl)-4-nitrobenzene

Refernces