7-Bromoquinolin-8-ol

Base Information

• Chemical Name: 7-Bromoquinolin-8-ol
• CAS No.: 13019-32-4
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.057
• Hs Code.: 2933499090
• Mol file: 13019-32-4.mol

Synonyms:7-Bromo-8-quinolinol;7-Bromo-8-hydroxyquinoline;7-bromo-quinolin-8-ol;8-quinolinol,7-bromo;7-Brom-chinolin-8-ol;

Chemical Property of 7-Bromoquinolin-8-ol

Chemical Property:

• Melting Point: 138-143 °C
• PSA: 33.12000
• LogP: 2.70290
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

7-Bromoquinolin-8-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 7-Bromoquinolin-8-ol

There total 8 articles about 7-Bromoquinolin-8-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

8-quinolinol (148-24-3,24804-14-6) + N-Brom-methylbutylamin (10218-87-8) → 7-bromo-8-hydroxyquinoline (13019-32-4)

Guidance literature:

In tetrachloromethane; at -8 - -2 ℃;

Reference yield: 85.0%

8-quinolinol (148-24-3,24804-14-6) → 7-bromo-8-hydroxyquinoline (13019-32-4)

Guidance literature:

With N-Bromosuccinimide; In chloroform; at 0 - 40 ℃; for 18h;

DOI:10.1080/10426507.2018.1488714

Reference yield: 37.0%

8-quinolinol (148-24-3,24804-14-6) → broxyquinoline (521-74-4) + 7-bromo-8-hydroxyquinoline (13019-32-4)

Guidance literature:

With bromine; In chloroform; at 20 ℃; for 48h; Darkness;

DOI:10.2174/1570180814666170504150050

upstream raw materials:

8-quinolinol

N-Brom-methylbutylamin

bromine

acetic acid

Downstream raw materials:

7-bromo-8-(methyloxy)quinoline

7-chloro-quinolin-8-ol

broxyquinoline

7,8-benzoquinoline