4-Methoxy-p-terphenyl

Base Information

• Chemical Name: 4-Methoxy-p-terphenyl
• CAS No.: 13041-66-2
• Molecular Formula: C19H16O
• Molecular Weight: 260.335
• DSSTox Substance ID: DTXSID30571596
• Nikkaji Number: J1.210.243G
• Wikidata: Q82459734
• Mol file: 13041-66-2.mol

Synonyms:13041-66-2;4-methoxy-p-terphenyl;SCHEMBL17283658;DTXSID30571596;1~4~-Methoxy-1~1~,2~1~:2~4~,3~1~-terphenyl

Chemical Property of 4-Methoxy-p-terphenyl

Chemical Property:

• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 260.120115130
• Heavy Atom Count: 20
• Complexity: 266

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of 4-Methoxy-p-terphenyl

There total 2 articles about 4-Methoxy-p-terphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

[1, 1'-biphenyl]-4-yl dimethylsulfamate (405201-85-6) + 4-methoxyphenyl magnesium bromide (13139-86-1) → 4,4'-Dimethoxybiphenyl (2132-80-1) + 4-methoxy-p-terphenyl (13041-66-2)

Guidance literature:

[1, 1'-biphenyl]-4-yl dimethylsulfamate; With iron(III) fluoride trihydrate; butyl magnesium bromide; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Reflux;

4-methoxyphenyl magnesium bromide; In tetrahydrofuran; for 8h; Reagent/catalyst; Inert atmosphere; Reflux;

DOI:10.1021/ol5024344

Reference yield: 13.0%

para-iodoanisole (696-62-8) + 1,4-Phenyldiboronic acid (4612-26-4) → 4-Phenylphenol (92-69-3) + [1,1';4',1'']terphenyl (92-94-4,94363-13-0) + 4-methoxy-p-terphenyl (13041-66-2) + 4,4-dimethoxy-1,1':4',1-terphenyl (13021-19-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; at 80 ℃; for 16h; Further byproducts given;

DOI:10.1016/S0040-4039(97)01552-9

Reference yield:

4-methoxy-p-terphenyl (13041-66-2) + 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane (380481-66-3) → 4-methyl-1,1':4',1'':4'',1'''-quaterphenyl (124110-29-8)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; cesium fluoride; 1,3-dicyclohexyl-1H-imidazol-3-ium chloride; sodium t-butanolate; In toluene; at 120 ℃; for 12h; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/ol502583h

upstream raw materials:

para-iodoanisole

1,4-Phenyldiboronic acid

[1, 1'-biphenyl]-4-yl dimethylsulfamate

4-methoxyphenyl magnesium bromide

Downstream raw materials:

4-methyl-1,1':4',1'':4'',1'''-quaterphenyl