3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside

Base Information

Chemical Name:3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside
CAS No.:72402-71-2
Molecular Formula:C36H31 F3 N2 O14
Molecular Weight:772.6315
Hs Code.:

3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside

Synonyms:NSC305989

Suppliers and Price of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:920.9°Cat760mmHg
Flash Point:510.7°C
Density:1.61g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside

There total 9 articles about 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 72384-25-9,73891-04-0,73891-07-3,76793-53-8,76793-57-2,77398-05-1,98103-08-3
1,5-anhydro-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-D-ribo-hex-1-enitol

: 21794-55-8
(+)-Daunomycinone

: 72402-71-2
7-O-(2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-D-ribo-hexopyranosyl)daunomycinone

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; benzene; at 50 ℃; for 3h;
DOI:10.1016/S0008-6215(00)84673-X

Reference yield:

: 76739-66-7
3,4-di-O-acetyl-D-rhamnal

: 72402-71-2
7-O-(2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-D-ribo-hexopyranosyl)daunomycinone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium azide ; 2.) lithium aluminium hydride / 1.) bortrifluorid etherate / 1.) acetonitrile; 2.) ether

2: 2.) pyridine

3: 61 percent / p-toluenesulfonic acid / benzene; CH₂Cl₂ / 3 h / 50 °C

With pyridine; lithium aluminium tetrahydride; sodium azide; toluene-4-sulfonic acid; boron trifluoride diethyl etherate; In dichloromethane; benzene;
DOI:10.1016/S0008-6215(00)84673-X

Reference yield:

: 21794-55-8
(+)-Daunomycinone

: 73891-04-0
2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-(trifluoroacetamido)-L-arabino-hex-1-enitol

: 73926-01-9
7-O-<2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-(trifluoroacetamido)-α-L-arabino-hexopyranosyl>daunomycinone

: 52583-24-1,62445-20-9,70629-86-6,70629-87-7,72402-71-2,73926-01-9,76793-42-5,76793-44-7,76793-45-8,76793-59-4,98103-09-4
7-O-<2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-(trifluoroacetamido)-β-L-arabino-hexopyranosyl>daunomycinone

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; benzene; at 20 ℃; for 2.5h; Yield given. Yields of byproduct given;
DOI:10.1016/S0008-6215(00)83831-8