ethyl 3-(3-propoxyphenyl)propanoate

Base Information

• Chemical Name: ethyl 3-(3-propoxyphenyl)propanoate
• CAS No.: 156175-82-5
• Molecular Formula: C₁₄H₂₀O₃
• Molecular Weight: 236.311
• Mol file: 156175-82-5.mol

Synonyms:

Chemical Property of ethyl 3-(3-propoxyphenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-(3-propoxyphenyl)propanoate

There total 3 articles about ethyl 3-(3-propoxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-trans-cinnamic acid (14755-02-3,588-30-7) → ethyl 3-(3-propoxyphenyl)propanoate (156175-82-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / hydrochloric acid / diethyl ether / 48 h / Heating

2: 89 percent / hydrogen / platinum oxide hydrate / aq. ethanol / 18 h / 1520 - 2280 Torr

3: potassium carbonate, potassium iodide / acetone / 48 h / Heating

With hydrogenchloride; hydrogen; potassium carbonate; potassium iodide; platinum(IV) oxide; In diethyl ether; ethanol; acetone;

DOI:10.1080/00397919608003878

Reference yield:

(E)-3-(3-hydroxyphenyl)acrylic acid ethyl ester (96251-92-2) → ethyl 3-(3-propoxyphenyl)propanoate (156175-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / hydrogen / platinum oxide hydrate / aq. ethanol / 18 h / 1520 - 2280 Torr

2: potassium carbonate, potassium iodide / acetone / 48 h / Heating

With hydrogen; potassium carbonate; potassium iodide; platinum(IV) oxide; In ethanol; acetone;

DOI:10.1080/00397919608003878

Reference yield:

3-(3-hydroxy-phenyl)propionic acid ethyl ester (34708-60-6) + propyl bromide (106-94-5) → ethyl 3-(3-propoxyphenyl)propanoate (156175-82-5)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 48h; Heating;

DOI:10.1080/00397919608003878

upstream raw materials:

3-(3-hydroxy-phenyl)propionic acid ethyl ester

propyl bromide

3-hydroxy-trans-cinnamic acid

(E)-3-(3-hydroxyphenyl)acrylic acid ethyl ester

Downstream raw materials:

1,2-dihydro-5-(3-propoxybenzyl)-2-thioxo-4(3H)-pyrimidinone

5-(3-propoxybenzyl)uracil

1-<(2-acetoxyethoxy)methyl>-5-(3-propoxybenzyl)uracil