96251-92-2Relevant articles and documents
Sequential Functionalization of meta-C-H and ipso-C-O Bonds of Phenols
Xu, Jiancong,Chen, Jingjing,Gao, Feng,Xie, Shuguang,Xu, Xiaohua,Jin, Zhong,Yu, Jin-Quan
, p. 1903 - 1907 (2019)
The use of a template as a linchpin motif in directed remote C-H functionalization is a versatile yet relatively underexplored strategy. We have developed a template-directed approach to realizing one-pot sequential palladium-catalyzed meta-selective C-H olefination of phenols, and nickel-catalyzed ipso-C-O activation and arylation. Thus, this bifunctional template converts phenols to synthetically useful 1,3-disubstituted arenes.
COMPOSITIONS FOR THE TREATMENT OF KIDNEY AND/OR LIVER DISEASE
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Paragraph 0086, (2016/10/04)
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of kidney and/or liver disease.
Benzocarbazoles dioxane derivatives, its preparation process and its use in medicine
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Paragraph 0539; 0541-0544, (2016/10/10)
The invention relates to a benzodioxane derivative, a preparation method thereof and application of the derivative in medicines. Specifically, the invention relates to a novel benzodioxane derivative shown as a formula (I), medial salt thereof or a medicine composition containing the derivative, and a preparation method of the derivative. The invention further relates to a use of the benzodioxane derivative and the medial salt thereof or the medicine composition containing the derivative in preparing therapeutic agent, especially GPR 40 agonist, and a drug for treating the diseases such as diabetes, metabolic disorders and the like, wherein each substituent group in the formula (I) is as defined in the description.