2,4-diphenyl-5-iodoxazole

Base Information

• Chemical Name: 2,4-diphenyl-5-iodoxazole
• CAS No.: 7019-31-0
• Molecular Formula: C₁₅H₁₀INO
• Molecular Weight: 347.155
• Mol file: 7019-31-0.mol

Synonyms:

Chemical Property of 2,4-diphenyl-5-iodoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-diphenyl-5-iodoxazole

There total 4 articles about 2,4-diphenyl-5-iodoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

O-(β-phenylethyl)phenylimidate triflic acid → 2,4-diphenyl-5-iodoxazole (7019-31-0) + 2,4-diphenyl-4,5-dihydro-1,3-oxazole (81187-69-1)

Guidance literature:

O-(β-phenylethyl)phenylimidate triflic acid; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

With 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione; potassium carbonate; In 1,2-dichloro-ethane; at 35 - 38 ℃; for 8h; Irradiation;

DOI:10.1002/ejoc.202000383

Reference yield: 39.0%

→ 2,4-diphenyl-5-iodoxazole (7019-31-0)

Guidance literature:

With 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione; potassium carbonate; In 1,2-dichloro-ethane; for 8h; Irradiation; Inert atmosphere;

Reference yield:

(2,4-Diphenyl-1,3-oxazole-5-yl)-mercuracetate (6117-57-3) → 2,4-diphenyl-5-iodoxazole (7019-31-0)

Guidance literature:

With iodine; In tetrachloromethane;

DOI:10.1002/jhet.5570180507

upstream raw materials:

(2,4-Diphenyl-1,3-oxazole-5-yl)-mercuracetate

2-phenylethanol

benzonitrile

Downstream raw materials:

5-Nitro-2,4-diphenyl-oxazole