Acetic acid, (4-chlorophenoxy)-, 2-(dithiocarboxy)hydrazide, monopotassium salt

Base Information

• Chemical Name: Acetic acid, (4-chlorophenoxy)-, 2-(dithiocarboxy)hydrazide, monopotassium salt
• CAS No.: 130946-73-5
• Molecular Formula: C9H9ClN2O2S2.K
• Molecular Weight: 314.858
• Mol file: 130946-73-5.mol

Synonyms:

Chemical Property of Acetic acid, (4-chlorophenoxy)-, 2-(dithiocarboxy)hydrazide, monopotassium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid, (4-chlorophenoxy)-, 2-(dithiocarboxy)hydrazide, monopotassium salt

There total 4 articles about Acetic acid, (4-chlorophenoxy)-, 2-(dithiocarboxy)hydrazide, monopotassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + (4-chlorophenoxy)acetic acid hydrazide (2381-75-1) → potassium (2-(4-chlorophenoxy)acetylhydrazinyl)dithioformate (130946-73-5)

Guidance literature:

With potassium hydroxide; In ethanol; Ambient temperature;

Reference yield:

4-Chlorophenoxyacetic acid (122-88-3) → potassium (2-(4-chlorophenoxy)acetylhydrazinyl)dithioformate (130946-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / conc. H₂SO₄ / methanol / 25 h / Heating

2: KOH / ethanol / 2 h

With potassium hydroxide; hydrazine hydrate; sulfuric acid; In methanol; ethanol;

DOI:10.1211/0022357011775307

Reference yield:

4-chloro-phenol (106-48-9,82344-39-6) → potassium (2-(4-chlorophenoxy)acetylhydrazinyl)dithioformate (130946-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / ethanol / 0.08 h

1.2: Reflux

1.3: 1 h / 20 °C

2.1: potassium hydroxide / ethanol / Reflux

With potassium carbonate; potassium hydroxide; In ethanol;

upstream raw materials:

carbon disulfide

(4-chlorophenoxy)acetic acid hydrazide

4-Chlorophenoxyacetic acid

4-chloro-phenol

Downstream raw materials:

3-(4-Chloro-phenoxymethyl)-6-(5-nitro-furan-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

5-(4-Chloro-phenoxymethyl)-4-{[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazole-3-thiol

4-Bromo-4-[5-(4-chloro-phenoxymethyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2,5-diphenyl-2,4-dihydro-pyrazol-3-one

4-[5-(4-Chloro-phenoxymethyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2,5-diphenyl-2,4-dihydro-pyrazol-3-one

Refernces

• 1、 -. "2,5-substituent-1,3,4-oxadiazole (thiadiazole) thioether derivatives as well as preparation method and application thereof". Paragraph 0057. . Retrieved 2017/04/03.
• 2、 Bhat,Bhat,Shenoy. "Synthesis and in-vitro antimicrobial activity of new 1,2,4-triazoles". . p. 267 - 272. Retrieved 2007/10/03.