1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-

Base Information

Chemical Name:1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-
CAS No.:131124-21-5
Molecular Formula:C13H13NO2S
Molecular Weight:247.318
Hs Code.:
DSSTox Substance ID:DTXSID90453107
Nikkaji Number:J2.367.407F
Wikidata:Q82274114

Synonyms:1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-;131124-21-5;1-Tosyl-2-vinyl-1H-pyrrole;SCHEMBL5776529;DTXSID90453107

Suppliers and Price of 1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:247.06669983
Heavy Atom Count:17
Complexity:363

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2C=CC=C2C=C

Technology Process of 1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]-

There total 6 articles about 1H-Pyrrole, 2-ethenyl-1-[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1779-49-3
Methyltriphenylphosphonium bromide

: 102619-05-6
1-(toluene-4-sulfonyl)-1H-pyrrole-2-carbaldehyde

: 131124-21-5
1-(toluene-4-sulfonyl)-2-vinyl-1H-pyrrole

Guidance literature:: Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 2h; Schlenk technique;

1-(toluene-4-sulfonyl)-1H-pyrrole-2-carbaldehyde; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1002/chem.201601283

Reference yield: 7.0%

: N-(2-Hydroxy-1-vinyl-but-3-enyl)-4-methyl-benzenesulfonamide

: 131124-21-5
1-(toluene-4-sulfonyl)-2-vinyl-1H-pyrrole

: 1-(Toluene-4-sulfonyl)-2-vinyl-2,5-dihydro-1H-pyrrole

Guidance literature:: dichloro bis(acetonitrile) palladium(II); In tetrahydrofuran; for 1.5h; Ambient temperature;
DOI:10.1039/c39940002531

Reference yield:

: 1003-29-8,254729-95-8
2-pyrrole aldehyde

: 131124-21-5
1-(toluene-4-sulfonyl)-2-vinyl-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / NaH / tetrahydrofuran / 13 h / 23 °C

2: 91 percent / BuLi / tetrahydrofuran; hexane / 12 h / -78 - 23 °C

With n-butyllithium; sodium hydride; In tetrahydrofuran; hexane;
DOI:10.1021/ja062355+