1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol

Base Information

• Chemical Name: 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol
• CAS No.: 118633-53-7
• Molecular Formula: C₁₀H₁₇BrO₃
• Molecular Weight: 265.147
• Mol file: 118633-53-7.mol

Synonyms:

Chemical Property of 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol

There total 3 articles about 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-vinylcyclohexyl acetate (6318-49-6) + N-bromoacetamide (79-15-2) → 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol (118633-53-7)

Guidance literature:

With sodium acetate; acetic acid; tert-butyl alcohol;

DOI:10.1021/ja01646a047

Reference yield:

1-acetoxy-1-ethynyl cyclohexane (5240-32-4) → 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol (118633-53-7)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium/calcium carbonate; pyridine / Hydrogenation

2: tert-butyl alcohol; aqueous sodium acetate; acetic acid

With pyridine; palladium on activated charcoal; Lindlar's catalyst; sodium acetate; acetic acid; tert-butyl alcohol;

DOI:10.1021/ja01646a047

Reference yield:

→ 1-(1-acetoxy-cyclohexyl)-2-bromo-ethanol (118633-53-7)

Guidance literature:

2-Brommethyl-1-oxa-spiro<2.5>octan, Eg. (1h, 95grad dann 2h, 65-75grad);

upstream raw materials:

1-vinylcyclohexyl acetate

N-bromoacetamide

1-acetoxy-1-ethynyl cyclohexane

Downstream raw materials:

1-(2-bromoacetyl)cyclohexyl acetate

2-hydroxy-1-(1-hydroxycyclohexyl)ethan-1-one

1-(2-acetoxyacetyl)cyclohexyl acetate