4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Base Information

Chemical Name:4-amino-1-phenyl-1H-pyrazole-5-carbonitrile
CAS No.:117767-00-7
Molecular Formula:C₁₀H₈N₄
Molecular Weight:184.2
Hs Code.:
European Community (EC) Number:807-798-7

Synonyms:4-amino-1-phenyl-1H-pyrazole-5-carbonitrile;117767-00-7;4-amino-2-phenyl-pyrazole-3-carbonitrile;starbld0015553

Suppliers and Price of 4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:184.074896272
Heavy Atom Count:14
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(=C(C=N2)N)C#N

Technology Process of 4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

There total 5 articles about 4-amino-1-phenyl-1H-pyrazole-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98534-76-0
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid, ethyl ester

: 117767-00-7
4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / dimethylformamide / 130 degC, 0.5 h, then 110 degC, 2 h

2: 86 percent / KOH / ethanol / Heating; heated just to reflux

3: SOCl₂ / toluene / 3 h / Heating

4: NaN₃ / acetone; H₂O / r.t. 1 h

5: 1. toluene, reflux, 30 min.; 2. reflux, 2 h

6: 59 percent / 30-32percent hydrobromic acid / acetic acid

With potassium hydroxide; thionyl chloride; sodium azide; hydrogen bromide; In ethanol; water; acetic acid; N,N-dimethyl-formamide; acetone; toluene;

Reference yield:

: 117766-98-0
5-Cyano-1-phenyl-1H-pyrazole-4-carbonyl chloride

: 117767-00-7
4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: NaN₃ / acetone; H₂O / r.t. 1 h

2: 1. toluene, reflux, 30 min.; 2. reflux, 2 h

3: 59 percent / 30-32percent hydrobromic acid / acetic acid

With sodium azide; hydrogen bromide; In water; acetic acid; acetone;

Reference yield:

: 98476-09-6
5-cyano-1-phenyl-1H-pyrazole-4-carboxylic acid,ethyl ester

: 117767-00-7
4-amino-1-phenyl-1H-pyrazole-5-carbonitrile

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / KOH / ethanol / Heating; heated just to reflux

2: SOCl₂ / toluene / 3 h / Heating

3: NaN₃ / acetone; H₂O / r.t. 1 h

4: 1. toluene, reflux, 30 min.; 2. reflux, 2 h

5: 59 percent / 30-32percent hydrobromic acid / acetic acid

With potassium hydroxide; thionyl chloride; sodium azide; hydrogen bromide; In ethanol; water; acetic acid; acetone; toluene;