Technology Process of C16H17NO4
There total 1 articles about C16H17NO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium acetate; acetic acid; zinc;
at 60 - 90 ℃;
for 2h;
DOI:10.1021/ja4025148
- Guidance literature:
-
C16H17NO4;
With
sulfuryl dichloride; bromine; acetic acid;
at 10 - 20 ℃;
for 5h;
With
water;
at 20 ℃;
for 1h;
regioselective reaction;
DOI:10.1021/ja4025148
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: acetic acid; bromine; sulfuryl dichloride / 5 h / 10 - 20 °C
1.2: 1 h / 20 °C
2.1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h
3.1: palladium 10% on activated carbon; formic acid; hydrogen / methanol / 2 h
4.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.17 h / 70 °C
4.2: 12 h / 20 °C
5.1: trifluoroacetic acid; hydrogenchloride / dichloromethane; water / 12 h / 20 °C
6.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; 4-methyl-morpholine / N,N-dimethyl-formamide / 0.17 h / 20 °C
6.2: 12 h / 20 °C
With
4-methyl-morpholine; hydrogenchloride; dmap; formic acid; sulfuryl dichloride; palladium 10% on activated carbon; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; bromine; acetic acid; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja4025148
