CrAsH

Base Information

Chemical Name:CrAsH
CAS No.:439791-28-3
Molecular Formula:C₂₅H₁₈As₂O₇S₄
Molecular Weight:708.521
Hs Code.:
Mol file:439791-28-3.mol

Synonyms:

Suppliers and Price of CrAsH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4'',5''-Bis(1,3,2-dithiarsolan-2-yl)-3'',6''-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9''-[9H]xanthene]-5-carboxylicAcid
2.5mg
$ 165.00

Total 1 raw suppliers

Chemical Property of CrAsH

Chemical Property:

Purity/Quality:: 4'',5''-Bis(1,3,2-dithiarsolan-2-yl)-3'',6''-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9''-[9H]xanthene]-5-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic Acid, is a biarsenical multi-use affinity probe with low non-specific fluorescence. It can be used for site-specific fluorescent labeling of recombinant proteins in living cells.

Technology Process of CrAsH

There total 4 articles about CrAsH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 5-carboxyfluorescein-4',5'-bis(mercuric trifluoroacetate)

: 540-63-6
ethane-1,2-dithiol

: 439791-28-3
4',5'-bis(1,3,2-dithioarsolan-2-yl)-fluorescein-5-carboxylic acid

Guidance literature:: 5-carboxyfluorescein-4',5'-bis(mercuric trifluoroacetate); With arsenic trichloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

ethane-1,2-dithiol; With palladium diacetate; In tetrahydrofuran; at 20 - 50 ℃; for 12h; Inert atmosphere;

With acetic acid; In tetrahydrofuran; chloroform; for 1.5h; Inert atmosphere;
DOI:10.1002/ardp.201500440

Reference yield: 28.0%

: C₂₅H₁₆Hg₂O₁₁

: 540-63-6
ethane-1,2-dithiol

: C₂₃H₁₅AsO₇S₂

: 439791-28-3
4',5'-bis(1,3,2-dithioarsolan-2-yl)-fluorescein-5-carboxylic acid

Guidance literature:: C₂₅H₁₆Hg₂O₁₁; With arsenic trichloride; N-ethyl-N,N-diisopropylamine; palladium diacetate; In 1-methyl-pyrrolidin-2-one; at 60 - 70 ℃; for 2h;

ethane-1,2-dithiol; In 1-methyl-pyrrolidin-2-one; phosphate buffer; acetone; pH=7; Further stages.;
DOI:10.1021/ja017687n

Reference yield:

: 76823-03-5
5-carboxyfluoroscein

: 439791-28-3
4',5'-bis(1,3,2-dithioarsolan-2-yl)-fluorescein-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / 8 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine; arsenic trichloride / tetrahydrofuran / 20 °C / Inert atmosphere

2.2: 12 h / 20 - 50 °C / Inert atmosphere

2.3: 1.5 h / Inert atmosphere

With arsenic trichloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran;
DOI:10.1002/ardp.201500440