(Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester

Base Information

• Chemical Name: (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester
• CAS No.: 93545-72-3
• Molecular Formula: C₂₃H₃₂N₂O₄
• Molecular Weight: 400.518
• Mol file: 93545-72-3.mol

Synonyms:

Chemical Property of (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester

There total 1 articles about (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl <1α,2α(Z),3α,4α>-7-<3-formyl-7-oxabicyclo<2.2.1>hept-2-yl>-5-heptenoate (104596-33-0) + 2-amino-N-phenylacetamide hydrochloride (4801-39-2) → (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester (93545-72-3,93603-23-7)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; for 4h; Ambient temperature; pH 4;

DOI:10.1021/jm00171a021

Reference yield:

(Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid methyl ester (93545-72-3,93603-23-7) → (Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid (93545-73-4,93603-24-8,128821-51-2)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; Yield given; Ambient temperature;

DOI:10.1021/jm00171a021

upstream raw materials:

methyl <1α,2α(Z),3α,4α>-7-<3-formyl-7-oxabicyclo<2.2.1>hept-2-yl>-5-heptenoate

2-amino-N-phenylacetamide hydrochloride

Downstream raw materials:

(Z)-7-{(1S,2R,3R,4R)-3-[(Phenylcarbamoylmethyl-amino)-methyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid