4801-39-2Relevant articles and documents
NovelN-transfer reagent for converting α-amino acid derivatives to α-diazo compounds
Lu, Guan-Han,Huang, Tzu-Chia,Hsueh, Hsiao-Chin,Yang, Shin-Cherng,Cho, Ting-Wei,Chou, Ho-Hsuan
supporting information, p. 4839 - 4842 (2021/05/25)
A novel universalN-transfer reagent for direct and effective transformation of α-amino ketones, acetamides, and esters to the corresponding α-diazo products under mild basic conditions has been developed. This one-step synthetic approach not only allows for generation of α-substituted-α-diazo carbonyl compounds from α-amino acid derivatives but also permits preparation of α-diazo dipeptides fromN-terminal dipeptides (32 examples, up to 91%).
2-substituted-4-site functionalized N (O, S)-quinazoline derivative and application thereof
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Paragraph 0073; 0080; 0081, (2020/07/02)
The invention relates to the technical field of medicine synthesis, and provides a 2-substituted-4-site functionalized N (O, S)-quinazoline derivative and an application thereof. The 2-substituted-4-site functionalized N (O, S)-quinazoline derivative prov
Process for preparation of an optically active amino acid amide
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, (2008/06/13)
The present invention relates to a process for the preparation of optically active amino acid amide. L-amino and D-amino acid amides are mixed in the presence of 0.5-4 equivalents of an aldehyde, relative to the quantity of amino acid amide, in the presen