Furan, 5-methyl-2-phenyl-3-(phenylsulfonyl)-

Base Information

• Chemical Name: Furan, 5-methyl-2-phenyl-3-(phenylsulfonyl)-
• CAS No.: 132268-96-3
• Molecular Formula: C17H14O3S
• Molecular Weight: 298.362
• Mol file: 132268-96-3.mol

Synonyms:

Chemical Property of Furan, 5-methyl-2-phenyl-3-(phenylsulfonyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Furan, 5-methyl-2-phenyl-3-(phenylsulfonyl)-

There total 5 articles about Furan, 5-methyl-2-phenyl-3-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-Benzenesulfonyl-2-iodomethyl-5-phenyl-2,3-dihydro-furan (132268-91-8) → 5-methyl-2-phenyl-3-(phenylsulfonyl)furan (132268-96-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In benzene; Heating;

Reference yield: 90.0%

4,5-dihydro-5-methylene-2-phenyl-3-(phenylsulfonyl)furan (146896-47-1) → 5-methyl-2-phenyl-3-(phenylsulfonyl)furan (132268-96-3)

Guidance literature:

With Amberlist; In benzene; for 3h; Ambient temperature;

DOI:10.1021/jo00058a011

Reference yield:

2-benzenesulfonyl-1-phenyl-pent-4-en-1-one (104869-91-2) → 5-methyl-2-phenyl-3-(phenylsulfonyl)furan (132268-96-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1)(NH₄)2S₂O₈

2: H₂O₂ / methanol / 4 h / Ambient temperature

3: 10percent NaHCO₃ / benzene / 7 h / Heating

4: 90 percent / amberlist / benzene / 3 h / Ambient temperature

With ammonium peroxydisulfate; Amberlist; dihydrogen peroxide; sodium hydrogencarbonate; In methanol; benzene;

DOI:10.1021/jo00058a011

upstream raw materials:

4-Benzenesulfonyl-2-iodomethyl-5-phenyl-2,3-dihydro-furan

4,5-dihydro-5-methylene-2-phenyl-3-(phenylsulfonyl)furan

2-benzenesulfonyl-1-phenyl-pent-4-en-1-one

4,5-dihydro-2-phenyl-5-<(phenylseleno)methyl>-3-(phenylsulfonyl)furan

Refernces

• 1、 Lee, Joe Wook,Oh, Dong Young. "I2-INDUCED ENOLETHERIFICATION OF α-ALLYL SUBSTITUTED β-KETO SULFONES; A ROUTE TO 3-PHENYLSULFONYL-2,5-DISUBSTITUTED FURANS". . p. 1417 - 1421. Retrieved 2007/10/02.