104869-91-2Relevant academic research and scientific papers
Highly enantioselective Pd-catalyzed allylic alkylations of acyclic ketones
Yan, Xiao-Xia,Liang, Chun-Gen,Zhang, Yan,Hong, Wei,Cao, Bo-Xun,Dai, Li-Xin,Hou, Xue-Long
, p. 6544 - 6546 (2005)
(Chemical Equation Presented) Pocket the difference: Highly enantioselective allylic alkylation of simple acyclic ketones is carried out by using a Pd catalyst with a "chiral pocket" ligand 1 (see scheme). The addition of a Lewis acid such as AgBr and the
Direct allylic substitution of allyl alcohols by carbon pronucleophiles in the presence of a palladium/carboxylic acid catalyst under neat conditions
Patil, Nitin T.,Yamamoto, Yoshinori
, p. 3101 - 3103 (2004)
The reaction of allylic alcohols with carbon pronucleophiles in the presence of the Pd(PPh3)4/carboxylic acid combined catalytic system, under neat conditions (without an organic solvent or without water as the solvent) enabled the direct allylation of the pronucleophiles, giving the corresponding allylated products in high yields.
Direct Allylation of Active Methylene Compounds with Allylic Alcohols by Use of Palladium/Phosphine-Borane Catalyst System
Shimizu, Aika,Hirata, Goki,Onodera, Gen,Kimura, Masanari
supporting information, p. 1954 - 1960 (2018/04/11)
The C?C bond formation between active methylene compounds and allylic alcohols has been newly developed by using a palladium complex as a catalyst together with a phosphine-borane ligand. The best phosphine-borane ligand for this direct allylation has bee
Metal-free desulfonylation reaction through visible-light photoredox catalysis
Yang, Deng-Tao,Meng, Qing-Yuan,Zhong, Jian-Ji,Xiang, Ming,Liu, Qiang,Wu, Li-Zhu
, p. 7528 - 7532 (2013/12/04)
The desulfonylation of β-arylketosulfones has been achieved in good to excellent yields by using 3-W blue LEDs light, 1 mol-% organic dye eosin Y bis(tetrabutylammonium salt) as photocatalyst, and diisopropylethylamine as reducing agent. Mechanistic studies demonstrate that oxidative quenching of the excited eosin Y by β-arylketosulfones plays a crucial role in the present photoredox catalytic cycle. Reductive desulfonylation is essential to enable to use of a sulfone as an auxiliary group. For reductive removal of sulfones, highly aggressive metal-containing reducing agents and harsh reaction conditions are often employed. In this paper, metal-free desulfonylation of β-arylketosulfones can be achieved efficiently at room temperature under visible-light irradiation.
NAD(P)+-NAD(P)H Models. 65. Photochemical Reductive Desulfonylation of β-Keto Sulfones with Hantzsch Ester
Fujii, Masayuki,Nakamura, Kaoru,Mekata, Hidevuki,Oka, Shinzaburo,Ohno, Atsuyoshi
, p. 495 - 500 (2007/10/02)
A new procedure for the reductive desulfonylation of β-keto sulfones is described.The reaction proceeds under a photochemical conditions with the Hantzsch ester in pyridine in the presence of ruthenium(II).Various functional groups are unaffected under the reaction conditions.Application of the procedure to the syntheses of certain natural products is also described.
