aminohexane geldanamycin

Base Information

• Chemical Name: aminohexane geldanamycin
• CAS No.: 485395-71-9
• Molecular Formula: C₃₄H₅₂N₄O₈
• Molecular Weight: 644.809
• Mol file: 485395-71-9.mol

Synonyms:

Chemical Property of aminohexane geldanamycin

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of aminohexane geldanamycin

There total 1 articles about aminohexane geldanamycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,6-Hexanediamine (124-09-4) + geldanmycin (30562-34-6) → aminohexane geldanamycin (485395-71-9)

Guidance literature:

In chloroform; at 20 ℃; for 20h;

Reference yield:

4-(trifluoromethyl)cinnamic acid (16642-92-5,87212-84-8,2062-26-2) + aminohexane geldanamycin (485395-71-9) → 17-(6-(4-trifluoromethylcinnamamido)hexylamino)-17-demethoxygeldanamycin

Guidance literature:

With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1111/cbdd.12371

Reference yield:

4-trifluoromethoxycinnamic acid (783-13-1) + aminohexane geldanamycin (485395-71-9) → 17-(6-(4-trifluoromethoxycinnamamido)hexylamino)-17-demethoxygeldanamycin

Guidance literature:

With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1111/cbdd.12371

upstream raw materials:

1,6-Hexanediamine

geldanmycin