C₂₉H₃₁ClN₄OS

Base Information

• Chemical Name: C₂₉H₃₁ClN₄OS
• CAS No.: 1396789-42-6
• Molecular Formula: C₂₉H₃₁ClN₄OS
• Molecular Weight: 519.11
• Mol file: 1396789-42-6.mol

Synonyms:

Chemical Property of C₂₉H₃₁ClN₄OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₁ClN₄OS

There total 4 articles about C₂₉H₃₁ClN₄OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C34H39ClN4O3S → C29H31ClN4OS (1396789-42-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 12h; Inert atmosphere;

DOI:10.3762/bjoc.8.94

Reference yield:

4-chlorothieno[2,3-c]pyridine-2-carboxylic acid (251996-86-8) + C23H31N3O2 (1060977-97-0) → C29H31ClN4OS (1396789-42-6)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.3762/bjoc.8.94

Reference yield:

4-bromopyridin (1120-87-2) → C29H31ClN4OS (1396789-42-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium carbonate; triphenylphosphine / water; toluene / 85 °C / Inert atmosphere

2.1: tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

2.2: 4 h / 0 - 20 °C

3.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere

With sodium carbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene; 1.1: Suzuki coupling;

DOI:10.3762/bjoc.8.94

upstream raw materials:

4-chlorothieno[2,3-c]pyridine-2-carboxylic acid

C₂₃H₃₁N₃O₂

4-bromopyridin

3-(pyridin-4-yl)-benzaldehyde