2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate

Base Information

• Chemical Name: 2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate
• CAS No.: 1037307-69-9
• Molecular Formula: C₂₉H₄₁Cl₃N₂O₁₀
• Molecular Weight: 684.011
• Mol file: 1037307-69-9.mol

Synonyms:

Chemical Property of 2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate

There total 1 articles about 2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H33Cl3N2O8 + di-tert-butyl dicarbonate (24424-99-5) → 2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate (1037307-69-9)

Guidance literature:

In tetrahydrofuran; water; benzene; for 5h;

DOI:10.1016/j.bmc.2008.03.020

Reference yield:

2,2,2-trichloroethyl (2S,3S)-3-O-[5-tert-butoxycarbonylamino-5-deoxy-2,3-O-(3-pentylidene)-β-D-ribofuranosyl]-2-benzyloxycarbonylamino-3-hydroxybutanoate (1037307-69-9) → C27H40N2O10 (1037307-70-2)

Guidance literature:

With ammonium chloride; zinc; In methanol; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2008.03.020

upstream raw materials:

di-tert-butyl dicarbonate

Downstream raw materials:

C₂₇H₄₀N₂O₁₀