Technology Process of 2,4,6-trimethylphenylchlorofluorenylborane
There total 1 articles about 2,4,6-trimethylphenylchlorofluorenylborane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
pentane;
byproducts: NaCl; 12 mmol mesityldichloroborane are added dropwise at 0°C to a stirred suspn. of 12 mmol fluorenyl sodium in pentane; the reaction mixt. is warmed up to room temp. and stirred for ca. 14 h; pptd. NaCl filtered off; solvent removed in vac., fractionation of the residual oil;
- Guidance literature:
-
With
lithium t-butyl(trimethylsilyl)amide;
In
toluene;
byproducts: LiCl, HN(t-Bu)SiMe3; to a soln. of 5.73 mmol C13H9BClC6H2Me3 and 21.4 mmol 3-hexine in toluene is added dropwise at -78°C a soln. of 5.73 mmol LiN(t-Bu)SiMe3 in toluene; the reaction mixt. is stirred at -40°C for 14 h, then at room temp. for 3 h; volatiles removed in vac.; residue recrystd. from toluene at -40°C;
- Guidance literature:
-
With
tetrahydrofuran;
In
tetrahydrofuran; pentane;
dropwise addn. of educt in THF to (t-Bu)3C6H2Li in pentane (-78°C, stirring); not isolated;
