4-amino-2-(dimethylamino)-7-pteridinethiol

Base Information

• Chemical Name: 4-amino-2-(dimethylamino)-7-pteridinethiol
• CAS No.: 118512-04-2
• Molecular Formula: C₈H₁₀N₆S
• Molecular Weight: 222.274
• Mol file: 118512-04-2.mol

Synonyms:

Chemical Property of 4-amino-2-(dimethylamino)-7-pteridinethiol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 4-amino-2-(dimethylamino)-7-pteridinethiol

There total 1 articles about 4-amino-2-(dimethylamino)-7-pteridinethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-amino-2-(dimethylamino)pteridin-7(8H)-one (26212-14-6) → 4-amino-2-(dimethylamino)pteridine-7-thiol (118512-04-2)

Guidance literature:

With tetraphosphorus decasulfide; In pyridine; at 80 ℃; for 7h;

DOI:10.1002/hlca.19880710305

Reference yield: 82.0%

4-amino-2-(dimethylamino)pteridine-7-thiol (118512-04-2) + methyl iodide (74-88-4) → 4-amino-2-(dimethylamino)-7-(methylthio)pteridine (118512-05-3)

Guidance literature:

With potassium hydroxide; Ambient temperature;

DOI:10.1002/hlca.19880710305

Reference yield:

4-amino-2-(dimethylamino)pteridine-7-thiol (118512-04-2) → 4-amino-2-(dimethylamino)-7-(methylthio)-6-(3-phenylpropionyl)pteridine

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / 4percent aq. KOH / Ambient temperature

2: 24 percent / FeSO₄*7H₂O, tert-butyl hydroperoxide / acetic acid; H₂O; H₂SO₄ / 7 h / Ambient temperature

With tert.-butylhydroperoxide; potassium hydroxide; iron(II) sulfate; In sulfuric acid; water; acetic acid;

DOI:10.1002/hlca.19880710305

upstream raw materials:

4-amino-2-(dimethylamino)pteridin-7(8H)-one

Downstream raw materials:

4-amino-2-(dimethylamino)-7-(methylthio)pteridine

Refernces