Technology Process of (E)-2-((E)-But-2-enyl)-2-(3,4-dimethoxy-phenyl)-hex-4-enoic acid
There total 1 articles about (E)-2-((E)-But-2-enyl)-2-(3,4-dimethoxy-phenyl)-hex-4-enoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium diisopropyl amide;
Yield given. Multistep reaction;
DOI:10.1246/cl.1981.1385
- Guidance literature:
-
Multi-step reaction with 7 steps
1: I2, KI, sat. NaHCO3
2: 1.) aq. NaOH; 2.) aq. HCl
3: 1.) aq. NaOH; 2.) NaIO4
4: NaBH4
5: 73 percent / O2 / Pd
6: t-BuOK / tetrahydrofuran
7: 7 percent / H2O / 180 °C
With
hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; sodium periodate; potassium tert-butylate; iodine; oxygen; sodium hydrogencarbonate; potassium iodide;
palladium;
In
tetrahydrofuran; water;
DOI:10.1246/cl.1981.1385
- Guidance literature:
-
Multi-step reaction with 8 steps
1: I2, KI, sat. NaHCO3
2: 1.) aq. NaOH; 2.) aq. HCl
3: 1.) aq. NaOH; 2.) NaIO4
4: NaBH4
5: 73 percent / O2 / Pd
6: t-BuOK / tetrahydrofuran
7: 7 percent / H2O / 180 °C
8: Li / liquid ammonia
With
hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; sodium periodate; potassium tert-butylate; iodine; oxygen; lithium; sodium hydrogencarbonate; potassium iodide;
palladium;
In
tetrahydrofuran; ammonia; water;
DOI:10.1246/cl.1981.1385
