Technology Process of C53H49N3P2
There total 5 articles about C53H49N3P2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) 2 N HCl, NaNO2, 2) NaN3 / 1) H2O, 30 min, 2) H2O, 3 h
2: 74 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 24 htmp
3: 92 percent / hydrazine hydrate / tetrahydrofuran; ethanol / 1) r.t., 16 h, 2) 70 deg C, 8 h
4: MgSO4 / diethyl ether / Ambient temperature
5: 2) NaBH4 / 1) ether, r.t., 12 h, 2) CH2Cl2, CH3OH, 0 deg C, 1.5 h
With
hydrogenchloride; sodium tetrahydroborate; sodium azide; magnesium sulfate; hydrazine hydrate; triphenylphosphine; sodium nitrite; diethylazodicarboxylate;
In
tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/jo00059a015
- Guidance literature:
-
Multi-step reaction with 2 steps
1: MgSO4 / diethyl ether / Ambient temperature
2: 2) NaBH4 / 1) ether, r.t., 12 h, 2) CH2Cl2, CH3OH, 0 deg C, 1.5 h
With
sodium tetrahydroborate; magnesium sulfate;
In
diethyl ether;
DOI:10.1021/jo00059a015
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 74 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 24 htmp
2: 92 percent / hydrazine hydrate / tetrahydrofuran; ethanol / 1) r.t., 16 h, 2) 70 deg C, 8 h
3: MgSO4 / diethyl ether / Ambient temperature
4: 2) NaBH4 / 1) ether, r.t., 12 h, 2) CH2Cl2, CH3OH, 0 deg C, 1.5 h
With
sodium tetrahydroborate; magnesium sulfate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/jo00059a015
