(2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Base Information

Chemical Name:(2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate
CAS No.:874301-15-2
Molecular Formula:C₅₀H₆₆O₈Si
Molecular Weight:823.155
Hs Code.:

(2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Synonyms:

Suppliers and Price of (2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

There total 2 articles about (2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (E)-ethyl 6-(4-methoxybenzyloxy)-3-(tributylstannyl)hex-2-enoate

: 874301-10-7
(E)-6-(tert-Butyl-diphenyl-silanyloxy)-4-iodo-1-((1S,2R,6R)-6-isopropenyl-2-methoxymethoxy-3-methyl-cyclohex-3-enyl)-hex-3-en-2-ol

: 874301-15-2
(2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Guidance literature:: (E)-ethyl 6-(4-methoxybenzyloxy)-3-(tributylstannyl)hex-2-enoate; (E)-6-(tert-Butyl-diphenyl-silanyloxy)-4-iodo-1-((1S,2R,6R)-6-isopropenyl-2-methoxymethoxy-3-methyl-cyclohex-3-enyl)-hex-3-en-2-ol; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) chloride; lithium chloride; In dimethyl sulfoxide; at 20 ℃; for 20h;

With tetrapropylammonium perruthennate; 4 A molecular sieve; 4-methylmorpholine N-oxide; In dichloromethane; acetonitrile; for 0.5h;
DOI:10.1021/jo0520691

Reference yield:

: (3E)-4-(tributylstannyl)-6-(tert-butyldiphenylsilyloxy)-1-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)hex-3-en-2-ol

: 874301-15-2
(2E,4E)-ethyl 4-(2-[tert-butyldiphenylsilyloxy]ethyl)-3-(3-(4-methoxybenzyloxy)propyl)-7-((1S,2R,6R)-2-(methoxymethoxy)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-enyl)-6-oxohepta-2,4-dienoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 75 percent / I₂ / CH₂Cl₂ / 0.08 h / -78 °C

2.1: LiCl; Pd(PPh₃)4; CuCl / dimethylsulfoxide / 20 h / 20 °C

2.2: 73 mg / 4 Angstroem molecular sieves; tetrapropylammonium perruthenate; 4-methylmorpholine N-oxide / CH₂Cl₂; acetonitrile / 0.5 h

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; copper(l) chloride; lithium chloride; In dichloromethane; dimethyl sulfoxide; 2.1: Stille coupling;
DOI:10.1021/jo0520691