Technology Process of C52H48N8O12
There total 12 articles about C52H48N8O12 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; diphenyl phosphoryl azide; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 20 ℃;
for 8h;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: Bromotrichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 4 h / 0 - 20 °C
2: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 8 h / 0 - 20 °C
3: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / dichloromethane / 3.5 h / 0 - 20 °C
4: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 8 h / 0 - 20 °C
5: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / dichloromethane / 3.5 h / 0 - 20 °C
6: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 10 h / 0 - 20 °C
7: hydrogenchloride / ethyl acetate / 6 h / 0 °C
8: dmap; diphenyl phosphoryl azide; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane / 8 h / 20 °C
With
hydrogenchloride; dmap; lithium hydroxide monohydrate; Bromotrichloromethane; diphenyl phosphoryl azide; water; benzotriazol-1-ol; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 8 h / 0 - 20 °C
2: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / dichloromethane / 3.5 h / 0 - 20 °C
3: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 8 h / 0 - 20 °C
4: N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate / dichloromethane / 3.5 h / 0 - 20 °C
5: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 10 h / 0 - 20 °C
6: hydrogenchloride / ethyl acetate / 6 h / 0 °C
7: dmap; diphenyl phosphoryl azide; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane / 8 h / 20 °C
With
hydrogenchloride; dmap; lithium hydroxide monohydrate; diphenyl phosphoryl azide; water; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate;